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NCT00493727 · ClinicalTrials.gov registry record · NA
Use of Mucomyst to Ameliorate Oxidant Stress in Diabetics With Proteinuria
A NA study, sponsored by US Department of Veterans Affairs.
- Completed
- Registry status
- NA
- Development phase
- 15
- Enrollment target
NCT00493727: Completed NA study, sponsored by US Department of Veterans Affairs.
NCT00493727 is a NA study that has completed, run by US Department of Veterans Affairs. The registered enrollment target is 15 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00493727, a NA study, has completed, sponsored by US Department of Veterans Affairs.
- COMPLETED
- Registry status
- NA
- Development phase
- 15 participants
- Enrollment target
Study Summary
The study will look at the effect of 30 days of treatment of 15 diabetics with proteinuria with N-acetylcysteine ( Mucomyst ) at a dose of 1 gm twice a day by mouth. The primary outcome that will be measured is change in the oxidant stress as measurable by changes in the serum level of isoprostane, Glutathione peroxidase, aconitase and Total oxidant stress. Secondary outcomes measured will be changes in proteinuria and kidney function as measured by spot urine pr/cr and estimated GFR by MDRD formula.
Interventions
- DRUG N-acetylcysteine(Mucomyst)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 15 participants |
| Start Date | 2006-09 |
| Est. Completion | 2007-12 |
| Phase | NA |
What the finished NCT00493727 record still lists
NCT00493727 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 1 intervention - of which N-acetylcysteine(Mucomyst) is the first listed.
NCT00493727 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00493727 about?
NCT00493727 is a clinical study titled "Use of Mucomyst to Ameliorate Oxidant Stress in Diabetics With Proteinuria". The study will look at the effect of 30 days of treatment of 15 diabetics with proteinuria with N-acetylcysteine ( Mucomyst ) at a dose of 1 gm twice a day by mouth. The primary outcome that will be measured is change in the oxidant stress as measurable by changes in the serum level of isoprostane, ...
What is the current status of trial NCT00493727?
This trial is currently completed. It is a NA study. The enrollment target is 15 participants. The study started on 2006-09. Estimated completion is 2007-12.
What interventions are being tested in trial NCT00493727?
The interventions under investigation include: N-acetylcysteine(Mucomyst) (DRUG).
Who is sponsoring clinical trial NCT00493727?
This trial is sponsored by US Department of Veterans Affairs, which has 632 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00493727's enrollment target sits among peer trials
15 1881st of 2000 higher than 92 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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