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NCT00487266 · ClinicalTrials.gov registry record · NA
Soft Tissue Biomechanical Behavior During Acupuncture in Low Back Pain
A NA study, sponsored by National Center for Complementary and Integrative Health (NCCIH).
- Completed
- Registry status
- NA
- Development phase
- 180
- Enrollment target
NCT00487266: Completed NA study, sponsored by National Center for Complementary and Integrative Health (NCCIH).
NCT00487266 is a NA study that has completed, run by National Center for Complementary and Integrative Health (NCCIH). The registered enrollment target is 180 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (87% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00487266, a NA study, has completed, sponsored by National Center for Complementary and Integrative Health (NCCIH).
- COMPLETED
- Registry status
- NA
- Development phase
- 180 participants
- Enrollment target
Study Summary
The goal of this proposal is to test the overall hypothesis that subjects with chronic or recurrent low back pain have an abnormal soft tissue response to acupuncture needling, and that this altered response is associated with abnormal perimuscular connective tissue structure and biomechanics. We will also test whether or not altered needling responses in low back pain are generalized, or localized to specific locations as predicted by traditional acupuncture theory. This proposal is part of a series of projects investigating the role of connective tissue in the mechanism of acupuncture and, in addition, constitutes a first step in examining the role of connective tissue in low back pain. Acupuncturists describe qualitatively different needling responses at locations believed to be "involved" in the patient's disease process. Although assessing abnormalities in the needling response is a fundamental aspect of acupuncture therapy, what constitutes a normal vs. abnormal needling response has never been studied quantitatively. Thus the nature of tissue changes underlying these phenomena remains unknown. We have recently developed a new in vivo technique based on ultrasound elastography that allows visualization and quantification of tissue displacement and strain patterns developed in tissues during needle manipulation in humans \[1\] (Appendix A). In this proposal, we will use ultrasound elastography, ultrasound image analysis and biomechanical modeling to perform 1) quantitative measurement of soft tissue behavior during needling and 2) detailed analysis of perimuscular connective tissue structure and biomechanics in human subjects with and without low back pain.
Interventions
- OTHER Acupuncture
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 180 participants |
| Start Date | 2006-09 |
| Est. Completion | 2010-08 |
| Phase | NA |
What the finished NCT00487266 record still lists
NCT00487266 is an interventional study that assigns participants to a tested intervention. The registered 180 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (87% lower).
The record links to 0 conditions, and to 1 intervention - of which Acupuncture is the first listed.
NCT00487266 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00487266 about?
NCT00487266 is a clinical study titled "Soft Tissue Biomechanical Behavior During Acupuncture in Low Back Pain". The goal of this proposal is to test the overall hypothesis that subjects with chronic or recurrent low back pain have an abnormal soft tissue response to acupuncture needling, and that this altered response is associated with abnormal perimuscular connective tissue structure and biomechanics. We wi...
What is the current status of trial NCT00487266?
This trial is currently completed. It is a NA study. The enrollment target is 180 participants. The study started on 2006-09. Estimated completion is 2010-08.
What interventions are being tested in trial NCT00487266?
The interventions under investigation include: Acupuncture (OTHER).
Who is sponsoring clinical trial NCT00487266?
This trial is sponsored by National Center for Complementary and Integrative Health (NCCIH), which has 203 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00487266's enrollment target sits among peer trials
180 586th of 2000 higher than 1,397 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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