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NCT00487162 · ClinicalTrials.gov registry record · NA
The Association Between Peri-Operative Hyperglycemia and Major Morbidity and Mortality
A NA study, sponsored by University of Medicine and Dentistry of New Jersey.
- Terminated
- Registry status
- NA
- Development phase
- 56
- Enrollment target
NCT00487162: Clinical Trial NA study, sponsored by University of Medicine and Dentistry of New Jersey.
NCT00487162 is a NA study that was terminated before completion, run by University of Medicine and Dentistry of New Jersey. The registered enrollment target is 56 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00487162, a NA study, was terminated before completion, sponsored by University of Medicine and Dentistry of New Jersey.
- TERMINATED
- Registry status
- NA
- Development phase
- 56 participants
- Enrollment target
Study Summary
Surgery induces a stress effect on the body partially through a catabolic energy state. In turn, glucose levels may rise to levels which have been associated with major morbidity (Golden, 1999) and mortality (Ouattara, 2005). An increasing body of evidence suggests that intensive insulin therapy for tight control of blood glucose levels in certain surgical and critical care patient populations may improve mortality and selected morbidity outcomes when compared to those patients receiving conventional insulin therapy and blood glucose management. More specifically, poor intra-operative blood glucose control is associated with worse outcome after cardiac surgery. Intensive insulin therapy with tight blood glucose control in surgical patients while in the ICU may reduce morbidity and mortality. Such outcome improvements would clearly provide benefits to patients, providers and payers. To date, there is scant research examining whether intensive insulin therapy for tight control of blood glucose in the perioperative period can alter outcomes for the non cardiac surgery population. The purpose of this study is to determine whether intensive insulin therapy for tight control of blood glucose in the perioperative period in non cardiac major surgery patients is associated with altered morbidity and mortality rates.
Interventions
- PROCEDURE intensive glycemic control
- DRUG conventional glycemic control
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 56 participants |
| Start Date | 2007-06 |
| Est. Completion | 2009-01 |
| Phase | NA |
Why NCT00487162 stopped before completion
NCT00487162 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 56 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower).
The record links to 0 conditions, and to 2 interventions - of which intensive glycemic control is the first listed.
NCT00487162 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00487162 about?
NCT00487162 is a clinical study titled "The Association Between Peri-Operative Hyperglycemia and Major Morbidity and Mortality". Surgery induces a stress effect on the body partially through a catabolic energy state. In turn, glucose levels may rise to levels which have been associated with major morbidity (Golden, 1999) and mortality (Ouattara, 2005). An increasing body of evidence suggests that intensive insulin therapy for...
What is the current status of trial NCT00487162?
This trial is currently terminated. It is a NA study. The enrollment target is 56 participants. The study started on 2007-06. Estimated completion is 2009-01.
What interventions are being tested in trial NCT00487162?
The interventions under investigation include: intensive glycemic control (PROCEDURE), conventional glycemic control (DRUG).
Who is sponsoring clinical trial NCT00487162?
This trial is sponsored by University of Medicine and Dentistry of New Jersey, which has 88 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00487162's enrollment target sits among peer trials
56 1262nd of 2000 higher than 737 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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