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NCT00486278 · ClinicalTrials.gov registry record · Phase 2

Haemophilia Patients With Inhibitors Being Treated for Acute Joint Bleeds

A Phase 2 study, sponsored by Novo Nordisk A/S.

Completed
Registry status
Phase 2
Development phase
51
Enrollment target

NCT00486278: Completed Phase 2 study, sponsored by Novo Nordisk A/S.

NCT00486278 is a Phase 2 study that has completed, run by Novo Nordisk A/S. The registered enrollment target is 51 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (62% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00486278, a Phase 2 study, has completed, sponsored by Novo Nordisk A/S.

COMPLETED
Registry status
Phase 2
Development phase
51 participants
Enrollment target

Study Summary

This trial is conducted in Africa, Asia, Europe, Japan, and North and South America. The aim of this trial is to evaluate the safety and efficacy of activated recombinant human factor VII analogue (vatreptocog alfa (activated)) in haemophilia patients with inhibitors.

Primary Outcome

Adverse event is defined as any untoward medical occurrence in a patient or clinical investigation patient administered a pharmaceutical product and which does not necessarily have to have a causal relationship with this treatment.

Interventions

  • DRUG vatreptacog alfa (activated)
  • DRUG eptacog alfa (activated)

Trial Details

FieldValue
Enrollment Target 51 participants
Start Date 2007-06
Est. Completion 2010-06
Phase Phase 2
Novo Nordisk A/S

431 total trials

What the finished NCT00486278 record still lists

NCT00486278 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 51 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (62% lower).

The record links to 0 conditions, and to 2 interventions - of which vatreptacog alfa (activated) is the first listed.

NCT00486278 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00486278 about?

NCT00486278 is a clinical study titled "Haemophilia Patients With Inhibitors Being Treated for Acute Joint Bleeds". This trial is conducted in Africa, Asia, Europe, Japan, and North and South America. The aim of this trial is to evaluate the safety and efficacy of activated recombinant human factor VII analogue (vatreptocog alfa (activated)) in haemophilia patients with inhibitors.

What is the current status of trial NCT00486278?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 51 participants. The study started on 2007-06. Estimated completion is 2010-06.

What interventions are being tested in trial NCT00486278?

The interventions under investigation include: vatreptacog alfa (activated) (DRUG), eptacog alfa (activated) (DRUG).

Who is sponsoring clinical trial NCT00486278?

This trial is sponsored by Novo Nordisk A/S, which has 431 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00486278's enrollment target sits among peer trials

51 1190th of 2000 higher than 806 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00486278, the US trial registry maintained by the National Library of Medicine. NCT00486278 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.