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NCT00481845 · ClinicalTrials.gov registry record · Phase 2

Phase 2 Anastrozole and Vandetanib (ZD6474) in Neoadjuvant Treatment of Postmenopausal Hormone Receptor-Positive Breast Cancer

A Phase 2 study, sponsored by Stanford University.

Terminated
Registry status
Phase 2
Development phase
1
Enrollment target

NCT00481845: Clinical Trial Phase 2 study, sponsored by Stanford University.

NCT00481845 is a Phase 2 study that was terminated before completion, run by Stanford University. The registered enrollment target is 1 participants. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00481845, a Phase 2 study, was terminated before completion, sponsored by Stanford University.

TERMINATED
Registry status
Phase 2
Development phase
1 participants
Enrollment target

Study Summary

In this study we plan to study the combination of ZD6474, a dual inhibitor of EGFR and VEGFR-2 with anastrozole in the neoadjuvant setting for patients with Stage I-III breast cancer. The aim is to overcome mechanisms of resistance and simultaneously block multiple critical signaling pathways known to stimulate breast cancer.

Interventions

  • DRUG Anastrozole
  • DRUG Vandetanib

Trial Details

FieldValue
Enrollment Target 1 participants
Start Date 2008-01
Est. Completion 2009-12
Phase Phase 2

Sponsor

Stanford University

1,744 total trials

What the Registry Record Tells You About NCT00481845

The ClinicalTrials.gov registry entry for NCT00481845 describes a study currently listed as terminated, categorized as Phase 2. The registered enrollment target is 1 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Stanford University, which has 1,744 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Anastrozole is the first listed.

NCT00481845 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00481845 about?

NCT00481845 is a clinical study titled "Phase 2 Anastrozole and Vandetanib (ZD6474) in Neoadjuvant Treatment of Postmenopausal Hormone Receptor-Positive Breast Cancer". In this study we plan to study the combination of ZD6474, a dual inhibitor of EGFR and VEGFR-2 with anastrozole in the neoadjuvant setting for patients with Stage I-III breast cancer. The aim is to overcome mechanisms of resistance and simultaneously block multiple critical signaling pathways known ...

What is the current status of trial NCT00481845?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 1 participants. The study started on 2008-01. Estimated completion is 2009-12.

What interventions are being tested in trial NCT00481845?

The interventions under investigation include: Anastrozole (DRUG), Vandetanib (DRUG).

Who is sponsoring clinical trial NCT00481845?

This trial is sponsored by Stanford University, which has 1,744 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.