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NCT00474279 · ClinicalTrials.gov registry record · Phase 1

Effects of an Oral GH Secretagogue (MK-677) on Body Composition and Functional Ability of Older Adults

A Phase 1 study, sponsored by University of Virginia.

Completed
Registry status
Phase 1
Development phase
72
Enrollment target

NCT00474279: Completed Phase 1 study, sponsored by University of Virginia.

NCT00474279 is a Phase 1 study that has completed, run by University of Virginia. The registered enrollment target is 72 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (20% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00474279, a Phase 1 study, has completed, sponsored by University of Virginia.

COMPLETED
Registry status
Phase 1
Development phase
72 participants
Enrollment target

Study Summary

The purpose of this study is to determine whether treatment of healthy older men and women with oral MK-677 for 12 months will enhance pulsatile GH release and increase mean GH and IGF-I concentrations into the range of young adults and will have favorable effects on body composition and functional ability on older adults.

Interventions

  • DRUG Orally active growth hormone secretagogue (MK-677)

Trial Details

FieldValue
Enrollment Target 72 participants
Start Date 1998-07
Est. Completion 2004-06
Phase Phase 1
University of Virginia

449 total trials

What the finished NCT00474279 record still lists

NCT00474279 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 72 participants, a relatively small participant target, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (20% higher).

The record links to 0 conditions, and to 1 intervention - of which Orally active growth hormone secretagogue (MK-677) is the first listed.

NCT00474279 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00474279 about?

NCT00474279 is a clinical study titled "Effects of an Oral GH Secretagogue (MK-677) on Body Composition and Functional Ability of Older Adults". The purpose of this study is to determine whether treatment of healthy older men and women with oral MK-677 for 12 months will enhance pulsatile GH release and increase mean GH and IGF-I concentrations into the range of young adults and will have favorable effects on body composition and functional ...

What is the current status of trial NCT00474279?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 72 participants. The study started on 1998-07. Estimated completion is 2004-06.

What interventions are being tested in trial NCT00474279?

The interventions under investigation include: Orally active growth hormone secretagogue (MK-677) (DRUG).

Who is sponsoring clinical trial NCT00474279?

This trial is sponsored by University of Virginia, which has 449 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00474279's enrollment target sits among peer trials

72 736th of 2000 higher than 1,254 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00474279, the US trial registry maintained by the National Library of Medicine. NCT00474279 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.