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NCT00473616 · ClinicalTrials.gov registry record · Phase 1
Phase I Single Ascending Dose/Multiple Ascending Dose in Patients Treated With AZD7762 and Irinotecan
A Phase 1 study, sponsored by AstraZeneca.
- Terminated
- Registry status
- Phase 1
- Development phase
- 60
- Enrollment target
NCT00473616: Clinical Trial Phase 1 study, sponsored by AstraZeneca.
NCT00473616 is a Phase 1 study that was terminated before completion, run by AstraZeneca. The registered enrollment target is 60 participants, roughly in line with the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00473616, a Phase 1 study, was terminated before completion, sponsored by AstraZeneca.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 60 participants
- Enrollment target
Study Summary
This is an open-label, multi-center, dose-escalation and safety expansion, Phase I study to evaluate the safety, tolerability, and pharmacokinectics and to investigate biomarker changes of AZD7762 administered as a single intravenous unit and in combination with irinotecan. The study is sponsored by AstraZeneca.
Interventions
- DRUG Irinotecan
- DRUG AZD7762
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2007-05 |
| Est. Completion | 2011-01 |
| Phase | Phase 1 |
Why NCT00473616 stopped before completion
NCT00473616 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, roughly in line with the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target.
The record links to 0 conditions, and to 2 interventions - of which Irinotecan is the first listed.
NCT00473616 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00473616 about?
NCT00473616 is a clinical study titled "Phase I Single Ascending Dose/Multiple Ascending Dose in Patients Treated With AZD7762 and Irinotecan". This is an open-label, multi-center, dose-escalation and safety expansion, Phase I study to evaluate the safety, tolerability, and pharmacokinectics and to investigate biomarker changes of AZD7762 administered as a single intravenous unit and in combination with irinotecan. The study is sponsored by...
What is the current status of trial NCT00473616?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 60 participants. The study started on 2007-05. Estimated completion is 2011-01.
What interventions are being tested in trial NCT00473616?
The interventions under investigation include: Irinotecan (DRUG), AZD7762 (DRUG).
Who is sponsoring clinical trial NCT00473616?
This trial is sponsored by AstraZeneca, which has 1,285 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00473616's enrollment target sits among peer trials
60 831st of 2000 higher than 1,106 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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