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NCT00466232 · ClinicalTrials.gov registry record · Phase 1
Phase I Study of Weekly Topotecan in Combination With Sorafenib in Treatment of Relapsed Small Cell Lung Cancer
A Phase 1 study, sponsored by HealthPartners Institute.
- Completed
- Registry status
- Phase 1
- Development phase
- 16
- Enrollment target
NCT00466232: Completed Phase 1 study, sponsored by HealthPartners Institute.
NCT00466232 is a Phase 1 study that has completed, run by HealthPartners Institute. The registered enrollment target is 16 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (73% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00466232, a Phase 1 study, has completed, sponsored by HealthPartners Institute.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 16 participants
- Enrollment target
Study Summary
The primary objective of this study is to determine the maximum tolerated dose of sorafenib up to the full active dose when combined with standard weekly dosing of topotecan in patients with recurrent small cell lung cancer and to characterize the toxicities associated with the combination of topotecan and sorafenib in this patient population
Interventions
- DRUG Topotecan
- DRUG Sorafenib
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 16 participants |
| Start Date | 2007-04 |
| Est. Completion | 2010-03 |
| Phase | Phase 1 |
What the finished NCT00466232 record still lists
NCT00466232 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 16 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (73% lower).
The record links to 0 conditions, and to 2 interventions - of which Topotecan is the first listed.
NCT00466232 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00466232 about?
NCT00466232 is a clinical study titled "Phase I Study of Weekly Topotecan in Combination With Sorafenib in Treatment of Relapsed Small Cell Lung Cancer". The primary objective of this study is to determine the maximum tolerated dose of sorafenib up to the full active dose when combined with standard weekly dosing of topotecan in patients with recurrent small cell lung cancer and to characterize the toxicities associated with the combination of topote...
What is the current status of trial NCT00466232?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 16 participants. The study started on 2007-04. Estimated completion is 2010-03.
What interventions are being tested in trial NCT00466232?
The interventions under investigation include: Topotecan (DRUG), Sorafenib (DRUG).
Who is sponsoring clinical trial NCT00466232?
This trial is sponsored by HealthPartners Institute, which has 146 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00466232's enrollment target sits among peer trials
16 1786th of 2000 higher than 203 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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