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NCT00457366 · ClinicalTrials.gov registry record · Phase 4
A Comparison Study of the Efficacy of Quetiapine and Haloperidol in Agitated Adults in Emergency Room
A Phase 4 study, sponsored by University of Southern California.
- Completed
- Registry status
- Phase 4
- Development phase
- 72
- Enrollment target
NCT00457366 is a Phase 4 study that has completed, run by University of Southern California. The registered enrollment target is 72 participants.
The verdict
NCT00457366, a Phase 4 study, has completed, sponsored by University of Southern California.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 72 participants
- Enrollment target
Study Summary
In the Psychiatric Emergency Room, agitated patients are treated routinely with an I.M. Haloperidol "cocktail" (Haloperidol 5 mg, Lorazepam 2 mg, Cogentin 2 mg), which has proved to be an effective treatment. However, since it is an intramuscular injection, it is more complicated and perhaps less acceptable to patients as well as more likely to cause EPS (extrapyramidal symptoms). Of late in our emergency room, we started using high dose Quetiapine 300 mg PO to replace the "cocktail" for treating agitation. It has shown promising results.
Interventions
- DRUG Haloperidol
- DRUG Quetiapine
- DRUG Lorazepam
- DRUG Cogentin
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 72 participants |
| Start Date | 2006-05 |
| Est. Completion | 2009-05 |
| Phase | Phase 4 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00457366
The ClinicalTrials.gov registry entry for NCT00457366 describes a study currently listed as completed, categorized as Phase 4. The registered enrollment target is 72 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Southern California, which has 617 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 4 interventions - of which Haloperidol is the first listed.
NCT00457366 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT00457366 about?
NCT00457366 is a clinical study titled "A Comparison Study of the Efficacy of Quetiapine and Haloperidol in Agitated Adults in Emergency Room". In the Psychiatric Emergency Room, agitated patients are treated routinely with an I.M. Haloperidol "cocktail" (Haloperidol 5 mg, Lorazepam 2 mg, Cogentin 2 mg), which has proved to be an effective treatment. However, since it is an intramuscular injection, it is more complicated and perhaps less ac...
What is the current status of trial NCT00457366?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 72 participants. The study started on 2006-05. Estimated completion is 2009-05.
What interventions are being tested in trial NCT00457366?
The interventions under investigation include: Haloperidol (DRUG), Quetiapine (DRUG), Lorazepam (DRUG), Cogentin (DRUG).
Who is sponsoring clinical trial NCT00457366?
This trial is sponsored by University of Southern California, which has 617 total clinical trials registered on ClinicalTrials.gov.
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