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NCT00454805 · ClinicalTrials.gov registry record · Phase 2
AZD2171 in Addition to Fulvestrant in Patients With Advanced Breast Cancer.
A Phase 2 study, sponsored by AstraZeneca.
- Completed
- Registry status
- Phase 2
- Development phase
- 75
- Enrollment target
NCT00454805: Completed Phase 2 study, sponsored by AstraZeneca.
NCT00454805 is a Phase 2 study that has completed, run by AstraZeneca. The registered enrollment target is 75 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (44% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00454805, a Phase 2 study, has completed, sponsored by AstraZeneca.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 75 participants
- Enrollment target
Study Summary
The purpose of this study is to determine whether AZD2171 can effectively improve time to tumour progression when added to fulvestrant in patients with advanced hormone sensitive breast cancer who progressed on prior hormonal therapy.
Primary Outcome
Number of months from randomisation until progressive disease based on RECIST (progression of target lesions, clear progression of existing non-target lesions or the appearance of one or more new lesions) or death in the absence of progression.
Interventions
- DRUG Fulvestrant
- DRUG AZD2171
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 75 participants |
| Start Date | 2007-03 |
| Est. Completion | 2016-04 |
| Phase | Phase 2 |
What the finished NCT00454805 record still lists
NCT00454805 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 75 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (44% lower).
The record links to 0 conditions, and to 2 interventions - of which Fulvestrant is the first listed.
NCT00454805 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00454805 about?
NCT00454805 is a clinical study titled "AZD2171 in Addition to Fulvestrant in Patients With Advanced Breast Cancer.". The purpose of this study is to determine whether AZD2171 can effectively improve time to tumour progression when added to fulvestrant in patients with advanced hormone sensitive breast cancer who progressed on prior hormonal therapy.
What is the current status of trial NCT00454805?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 75 participants. The study started on 2007-03. Estimated completion is 2016-04.
What interventions are being tested in trial NCT00454805?
The interventions under investigation include: Fulvestrant (DRUG), AZD2171 (DRUG).
Who is sponsoring clinical trial NCT00454805?
This trial is sponsored by AstraZeneca, which has 1,285 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00454805's enrollment target sits among peer trials
75 900th of 2000 higher than 1,081 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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