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NCT00454493 · ClinicalTrials.gov registry record · NA
The Effect of Fish Oil Supplementation on Endothelial Function, Heart Rate Variability and Intimal Media Thickness of Patients With Coronary Artery Disease
A NA study, sponsored by Olive View-UCLA Education & Research Institute.
- Completed
- Registry status
- NA
- Development phase
- 71
- Enrollment target
NCT00454493 is a NA study that has completed, run by Olive View-UCLA Education & Research Institute. The registered enrollment target is 71 participants.
The verdict
NCT00454493, a NA study, has completed, sponsored by Olive View-UCLA Education & Research Institute.
- COMPLETED
- Registry status
- NA
- Development phase
- 71 participants
- Enrollment target
Study Summary
The purpose of this study is to investigate whether there is a difference in endothelial function, heart rate variability and carotid intimal media thickness in patients with coronary artery disease who are receiving fish oil therapy. One hundred patients with established coronary artery disease by coronary angiography will undergo randomization for enrollment in the study. Baseline evaluation will include assessment of brachial artery endothelial function, heart rate variability and carotid intimal media thickness. Evaluation of the endothelial function of the brachial artery will be elucidated by inflation of a blood pressure cuff around the arm for five minutes and measuring blood vessel dynamics after release of the cuff. Heart rate variability will be evaluated by 24 hour holter monitoring and analysis by standard protocol. Carotid intimal media thickness will be evaluated by ultrasound measurements guided by predetermined protocol. Patients will then be randomized to a highly purified fish oil, Omacor, 1 gram twice a day or placebo. Brachial artery ultrasound and holter monitoring will be repeated at 2 months. Carotid ultrasound will be repeated at the end of the study at 12 months.
Interventions
- DRUG Omacor (omega-3-acid ethyl esters)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 71 participants |
| Start Date | 2006-08 |
| Est. Completion | 2008-12 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00454493
The ClinicalTrials.gov registry entry for NCT00454493 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 71 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Olive View-UCLA Education & Research Institute, which has 11 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Omacor (omega-3-acid ethyl esters) is the first listed.
NCT00454493 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT00454493 about?
NCT00454493 is a clinical study titled "The Effect of Fish Oil Supplementation on Endothelial Function, Heart Rate Variability and Intimal Media Thickness of Patients With Coronary Artery Disease". The purpose of this study is to investigate whether there is a difference in endothelial function, heart rate variability and carotid intimal media thickness in patients with coronary artery disease who are receiving fish oil therapy. One hundred patients with established coronary artery disease by...
What is the current status of trial NCT00454493?
This trial is currently completed. It is a NA study. The enrollment target is 71 participants. The study started on 2006-08. Estimated completion is 2008-12.
What interventions are being tested in trial NCT00454493?
The interventions under investigation include: Omacor (omega-3-acid ethyl esters) (DRUG).
Who is sponsoring clinical trial NCT00454493?
This trial is sponsored by Olive View-UCLA Education & Research Institute, which has 11 total clinical trials registered on ClinicalTrials.gov.
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