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NCT00454155 · ClinicalTrials.gov registry record · Phase 1
Study of Opebacan in Patients Undergoing Myeloablative Allogeneic Hematopoietic Stem Cell Transplantation (HSCT)
A Phase 1 study, sponsored by Xoma (US).
- Terminated
- Registry status
- Phase 1
- Development phase
- 6
- Enrollment target
NCT00454155: Clinical Trial Phase 1 study, sponsored by Xoma (US).
NCT00454155 is a Phase 1 study that was terminated before completion, run by Xoma (US). The registered enrollment target is 6 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (90% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00454155, a Phase 1 study, was terminated before completion, sponsored by Xoma (US).
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 6 participants
- Enrollment target
Study Summary
The objectives of this study are as follows: To demonstrate the safety of escalating doses of opebacan in subjects undergoing myeloablative allogeneic Hematopoietic Stem Cell Transplantation To determine the pharmacokinetics of opebacan in subjects undergoing myeloablative allogeneic Hematopoietic Stem Cell Transplantation To determine if IV administration of opebacan is associated with changes in biological markers for inflammation To develop preliminary descriptive data on the occurrence and severity of Hematopoietic Stem Cell Transplantation related complications, including aGvHD
Interventions
- DRUG Opebacan
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 6 participants |
| Start Date | 2007-02 |
| Est. Completion | 2010-06 |
| Phase | Phase 1 |
Why NCT00454155 stopped before completion
NCT00454155 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 6 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (90% lower).
The record links to 0 conditions, and to 1 intervention - of which Opebacan is the first listed.
NCT00454155 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00454155 about?
NCT00454155 is a clinical study titled "Study of Opebacan in Patients Undergoing Myeloablative Allogeneic Hematopoietic Stem Cell Transplantation (HSCT)". The objectives of this study are as follows: To demonstrate the safety of escalating doses of opebacan in subjects undergoing myeloablative allogeneic Hematopoietic Stem Cell Transplantation To determine the pharmacokinetics of opebacan in subjects undergoing myeloablative allogeneic Hematopoietic...
What is the current status of trial NCT00454155?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 6 participants. The study started on 2007-02. Estimated completion is 2010-06.
What interventions are being tested in trial NCT00454155?
The interventions under investigation include: Opebacan (DRUG).
Who is sponsoring clinical trial NCT00454155?
This trial is sponsored by Xoma (US), which has 20 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00454155's enrollment target sits among peer trials
6 1974th of 2000 higher than 12 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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