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NCT00453700 · ClinicalTrials.gov registry record
Prevalence of Chagas Disease in Immigrant Patients With Conduction Abnormalities on Electrocardiogram
A clinical trial, sponsored by Olive View-UCLA Education & Research Institute.
- Completed
- Registry status
- 327
- Enrollment target
NCT00453700 is a clinical trial that has completed, run by Olive View-UCLA Education & Research Institute. The registered enrollment target is 327 participants.
The verdict
NCT00453700 has completed, sponsored by Olive View-UCLA Education & Research Institute.
- COMPLETED
- Registry status
- 327 participants
- Enrollment target
Study Summary
Chagas disease is endemic to the Americas, infecting between 16-18 million individuals. In immigrant populations in the United States from endemic areas, it is estimated up to 4.9% may be asymptomatic carriers of Trypanosoma cruzi, the organism which causes Chagas disease. Between 10-20% of these patients progress to development of end-stage cardiomyopathy with a high associated morbidity. Following acute disease, patients enter into an indeterminate phase which can last 10-20 years. The earliest sign of cardiac involvement usually is electrocardiogram abnormalities. The most common abnormality is right bundle branch block (RBBB), followed by left anterior fascicular block (LAFB), and left bundle branch block (LBBB). Recent studies have shown that treatment of patients at this stage with antiparasitics may delay the progression of overt cardiomyopathy. At the University of California, Los Angeles, there is a large population of immigrant patients from countries endemic to Chagas disease. The researchers propose that screening patients with conduction abnormalities on electrocardiogram may be a potentially useful method to identify patients with early cardiac manifestations of Chagas disease. The researchers hope to enroll approximately 300 individuals with RBBB, LAFB or LBBB on electrocardiogram to determine the incidence of Chagas disease in this patient population.
Interventions
- PROCEDURE Trypanosoma cruzi serology
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 327 participants |
| Start Date | 2007-01 |
| Est. Completion | 2010-12 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00453700
The ClinicalTrials.gov registry entry for NCT00453700 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 327 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Olive View-UCLA Education & Research Institute, which has 11 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Trypanosoma cruzi serology is the first listed.
NCT00453700 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT00453700 about?
NCT00453700 is a clinical study titled "Prevalence of Chagas Disease in Immigrant Patients With Conduction Abnormalities on Electrocardiogram". Chagas disease is endemic to the Americas, infecting between 16-18 million individuals. In immigrant populations in the United States from endemic areas, it is estimated up to 4.9% may be asymptomatic carriers of Trypanosoma cruzi, the organism which causes Chagas disease. Between 10-20% of these pa...
What is the current status of trial NCT00453700?
This trial is currently completed. The enrollment target is 327 participants. The study started on 2007-01. Estimated completion is 2010-12.
What interventions are being tested in trial NCT00453700?
The interventions under investigation include: Trypanosoma cruzi serology (PROCEDURE).
Who is sponsoring clinical trial NCT00453700?
This trial is sponsored by Olive View-UCLA Education & Research Institute, which has 11 total clinical trials registered on ClinicalTrials.gov.
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