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NCT00452283 · ClinicalTrials.gov registry record
Changes in Eye Pressure and Anterior Chamber Depth With Oral Endothelin Antagonist Therapy
A clinical trial, sponsored by University of Colorado, Denver.
- Completed
- Registry status
- 23
- Enrollment target
NCT00452283: Completed study, sponsored by University of Colorado, Denver.
NCT00452283 is a clinical trial that has completed, run by University of Colorado, Denver. The registered enrollment target is 23 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00452283 has completed, sponsored by University of Colorado, Denver.
- COMPLETED
- Registry status
- 23 participants
- Enrollment target
Study Summary
There is growing evidence that a cause of glaucoma is linked to circulatory problems and poor auto-regulation of blood flow to the optic nerve. Pulmonary hypertension (PH)is a disease characterized by low oxygen levels in the blood and altered blood circulation. The decrease in oxygen delivery to the optic nerve could lead to the loss of nerve fiber layer(NFL)in the retina and the resulting visual field compromise. This situation is characteristic of glaucoma. The ability to identify NFL thinning early could lead to earlier diagnosis of glaucoma and more effective treatment to limit dysfunction from visual field loss. We hypothesize that the rate of structural damage to the NFL, a feature of glaucoma, is higher in patients with PH than expected in healthy populations lacking this disease.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 23 participants |
| Start Date | 2007-03 |
| Est. Completion | 2011-05 |
What the finished NCT00452283 record still lists
NCT00452283 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 23 participants, a relatively small participant target.
The record links to 0 conditions, and to 0 interventions.
NCT00452283 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00452283 about?
NCT00452283 is a clinical study titled "Changes in Eye Pressure and Anterior Chamber Depth With Oral Endothelin Antagonist Therapy". There is growing evidence that a cause of glaucoma is linked to circulatory problems and poor auto-regulation of blood flow to the optic nerve. Pulmonary hypertension (PH)is a disease characterized by low oxygen levels in the blood and altered blood circulation. The decrease in oxygen delivery to th...
What is the current status of trial NCT00452283?
This trial is currently completed. The enrollment target is 23 participants. The study started on 2007-03. Estimated completion is 2011-05.
Who is sponsoring clinical trial NCT00452283?
This trial is sponsored by University of Colorado, Denver, which has 1,283 total clinical trials registered on ClinicalTrials.gov.
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