Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT00451841 · ClinicalTrials.gov registry record
Exhaled Breath Condensate pH in Patients With Cough Caused by Gastroesophageal Reflux
A clinical trial, sponsored by University of Massachusetts, Worcester.
- Terminated
- Registry status
- 30
- Enrollment target
NCT00451841: Clinical Trial study, sponsored by University of Massachusetts, Worcester.
NCT00451841 is a clinical trial that was terminated before completion, run by University of Massachusetts, Worcester. The registered enrollment target is 30 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00451841 was terminated before completion, sponsored by University of Massachusetts, Worcester.
- TERMINATED
- Registry status
- 30 participants
- Enrollment target
Study Summary
Cough is the most common complaint for which patients seek medical attention in the United States, accounting for approximately 1 billion dollars in health care expenses annually. Gastroesophageal reflux disease (GERD) is the sole cause of chronic cough in up to 20-40% of all cases. The majority of these patients with GERD-induced cough have no classic "heartburn" symptoms, so this important cause of cough can thus be difficult to detect. Our hypothesis is that changes in exhaled breath condensate (EBC) pH can be used as a sensitive and non-invasive marker to identify subjects with cough caused by acid reflux.
Primary Outcome
Determine the sensitivity of esophageal PH changes between the group with GERD and the group without GERD.
Interventions
- DEVICE RTube Exhaled Breath Condensate Collection System
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2007-03 |
| Est. Completion | 2013-06 |
Why NCT00451841 stopped before completion
NCT00451841 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 30 participants, a relatively small participant target.
The record links to 0 conditions, and to 1 intervention - of which RTube Exhaled Breath Condensate Collection System is the first listed.
NCT00451841 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00451841 about?
NCT00451841 is a clinical study titled "Exhaled Breath Condensate pH in Patients With Cough Caused by Gastroesophageal Reflux". Cough is the most common complaint for which patients seek medical attention in the United States, accounting for approximately 1 billion dollars in health care expenses annually. Gastroesophageal reflux disease (GERD) is the sole cause of chronic cough in up to 20-40% of all cases. The majority of ...
What is the current status of trial NCT00451841?
This trial is currently terminated. The enrollment target is 30 participants. The study started on 2007-03. Estimated completion is 2013-06.
What interventions are being tested in trial NCT00451841?
The interventions under investigation include: RTube Exhaled Breath Condensate Collection System (DEVICE).
Who is sponsoring clinical trial NCT00451841?
This trial is sponsored by University of Massachusetts, Worcester, which has 240 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT00977977 · 30 participants · Phase 2
Rituximab Plus Cyclosporine in Idiopathic Membranous Nephropathy
- NCT01459107 · 30 participants · Phase 2
Human Upper Extremity Allotransplantation
- NCT01666080 · 30 participants · NA
Second or Greater Allogeneic Hematopoietic Stem Cell Transplant Using Reduced Intensity Conditioning (RIC)
- NCT01720836 · 30 participants · Phase 1
Study of the Immune Response of MUC1 (Mucin1) Peptide Vaccine for Non-small Cell Lung Cancer
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia