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NCT00450138 · ClinicalTrials.gov registry record · Phase 1
Open Label, Phase I ZD6474 Head and Neck Cancer Study
A Phase 1 study, sponsored by Sanofi.
- Completed
- Registry status
- Phase 1
- Development phase
- 48
- Enrollment target
NCT00450138: Completed Phase 1 study, sponsored by Sanofi.
NCT00450138 is a Phase 1 study that has completed, run by Sanofi. The registered enrollment target is 48 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (20% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00450138, a Phase 1 study, has completed, sponsored by Sanofi.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 48 participants
- Enrollment target
Study Summary
The purpose of this study is to determine the maximum tolerated dose of ZD6474 given in combination with radiation or in combination with chemotherapy and radiation in patients with squamous cell carcinoma of the head and neck.
Interventions
- DRUG Cisplatin
- RADIATION Radiation
- DRUG ZD6474 (vandetanib)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 48 participants |
| Start Date | 2006-12 |
| Est. Completion | 2011-11 |
| Phase | Phase 1 |
What the finished NCT00450138 record still lists
NCT00450138 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 48 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (20% lower).
The record links to 0 conditions, and to 3 interventions - of which Cisplatin is the first listed.
NCT00450138 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00450138 about?
NCT00450138 is a clinical study titled "Open Label, Phase I ZD6474 Head and Neck Cancer Study". The purpose of this study is to determine the maximum tolerated dose of ZD6474 given in combination with radiation or in combination with chemotherapy and radiation in patients with squamous cell carcinoma of the head and neck.
What is the current status of trial NCT00450138?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 48 participants. The study started on 2006-12. Estimated completion is 2011-11.
What interventions are being tested in trial NCT00450138?
The interventions under investigation include: Cisplatin (DRUG), Radiation (RADIATION), ZD6474 (vandetanib) (DRUG).
Who is sponsoring clinical trial NCT00450138?
This trial is sponsored by Sanofi, which has 713 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00450138's enrollment target sits among peer trials
48 1025th of 2000 higher than 948 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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