Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT00447187 · ClinicalTrials.gov registry record · Phase 3
Study to Assess the Efficacy and Safety of LX201 for Prevention of Corneal Allograft Rejection Episodes and Graft Failure in Subjects at Increased Immunological Risk
A Phase 3 study, sponsored by Lux Biosciences.
- Terminated
- Registry status
- Phase 3
- Development phase
- 368
- Enrollment target
NCT00447187: Clinical Trial Phase 3 study, sponsored by Lux Biosciences.
NCT00447187 is a Phase 3 study that was terminated before completion, run by Lux Biosciences. The registered enrollment target is 368 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (52% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00447187, a Phase 3 study, was terminated before completion, sponsored by Lux Biosciences.
- TERMINATED
- Registry status
- Phase 3
- Development phase
- 368 participants
- Enrollment target
Study Summary
This was a pivotal trial to determine whether LX201 reduces the likelihood of a graft rejection episode following corneal transplantation in patients at high immunological risk for rejection.
Interventions
- OTHER Placebo
- DRUG LX201
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 368 participants |
| Start Date | 2007-04 |
| Est. Completion | 2010-11 |
| Phase | Phase 3 |
Why NCT00447187 stopped before completion
NCT00447187 is an interventional study that assigns participants to a tested intervention. The registered 368 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (52% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT00447187 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00447187 about?
NCT00447187 is a clinical study titled "Study to Assess the Efficacy and Safety of LX201 for Prevention of Corneal Allograft Rejection Episodes and Graft Failure in Subjects at Increased Immunological Risk". This was a pivotal trial to determine whether LX201 reduces the likelihood of a graft rejection episode following corneal transplantation in patients at high immunological risk for rejection.
What is the current status of trial NCT00447187?
This trial is currently terminated. It is a Phase 3 study. The enrollment target is 368 participants. The study started on 2007-04. Estimated completion is 2010-11.
What interventions are being tested in trial NCT00447187?
The interventions under investigation include: Placebo (OTHER), LX201 (DRUG).
Who is sponsoring clinical trial NCT00447187?
This trial is sponsored by Lux Biosciences, which has 7 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00447187's enrollment target sits among peer trials
368 996th of 2000 higher than 1,003 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT04675476 · 368 participants · NA
A Patient and Provider Intervention to Address Health Disparities in Lung Cancer Screening
- NCT05215353 · 368 participants · Phase 4
A Study Comparing Music Therapy and Cognitive Behavioral Therapy for Anxiety in Cancer Survivors
- NCT06182397 · 368 participants · NA
Sirolimus Coated BALloon Versus Standard Balloon Angioplasty in The Treatment of Below The Knee Arterial Disease
- NCT06629610 · 368 participants · NA
Diet and Active Lifestyle - Yuuyaraq (The Yup'ik Way of Life)
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia