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NCT00446706 · ClinicalTrials.gov registry record
Estimation of Intrinsic Positive End-Expiratory Pressure (PEEP) in Acute Respiratory Distress Syndrome (ARDS)
A clinical trial, sponsored by Texas Tech University Health Sciences Center, El Paso.
- Completed
- Registry status
- 6
- Enrollment target
NCT00446706: Completed study, sponsored by Texas Tech University Health Sciences Center, El Paso.
NCT00446706 is a clinical trial that has completed, run by Texas Tech University Health Sciences Center, El Paso. The registered enrollment target is 6 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00446706 has completed, sponsored by Texas Tech University Health Sciences Center, El Paso.
- COMPLETED
- Registry status
- 6 participants
- Enrollment target
Study Summary
ARDS (Acute Respiratory Distress Syndrome) is a condition of severe inflammation and excess fluids in the lungs that impairs their function of oxygen uptake to the point of needing a ventilator (breathing machine) to help them obtain enough oxygen into the body. Because of the high amounts of gas that the ventilator has to give to these patients, high pressures may develop deep into the lungs and produce complications for the patient. However, physicians sometimes cannot recognize it because it requires special equipment to measure pressure deep in the lungs. The goal of this study is to determine if the amount of this pressure can be calculated using mathematical formulas and the routine numbers provided by ventilators. The study consists on making the conventional measurement of this deep pressure and at the same time calculate this same pressure from other measurements that the ventilator routinely provides, to see if the calculated value can replace the more complicated conventional measurement. The measurements will be done by: 1. placing a small device along the tubing connecting the patient to the ventilator; 2. giving medicines to relax the muscles (if the patient is not already receiving them); and 3. making the ventilator hold the patient's breath for a few seconds to take measurements. This is repeated after the breathing rate of the ventilator is increased or decreased mildly. Risks related to the medicine to be used and the measuring maneuvers are rare but include transient narrowing of windpipes, transiently low heart rate, blood pressure or blood oxygen, and allergic reactions. This is not a treatment. The information obtained during the study will be shared with the treating doctors who may find it useful to make adjustments to the ventilator. The patient may receive no direct benefit from being in this study; however, the findings may contribute to better care for this kind of patients in the future.
Primary Outcome
Bias and its standard deviation
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 6 participants |
| Start Date | 2004-01 |
| Est. Completion | 2007-04 |
What the finished NCT00446706 record still lists
NCT00446706 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 6 participants, a relatively small participant target.
The record links to 0 conditions, and to 0 interventions.
NCT00446706 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00446706 about?
NCT00446706 is a clinical study titled "Estimation of Intrinsic Positive End-Expiratory Pressure (PEEP) in Acute Respiratory Distress Syndrome (ARDS)". ARDS (Acute Respiratory Distress Syndrome) is a condition of severe inflammation and excess fluids in the lungs that impairs their function of oxygen uptake to the point of needing a ventilator (breathing machine) to help them obtain enough oxygen into the body. Because of the high amounts of gas th...
What is the current status of trial NCT00446706?
This trial is currently completed. The enrollment target is 6 participants. The study started on 2004-01. Estimated completion is 2007-04.
Who is sponsoring clinical trial NCT00446706?
This trial is sponsored by Texas Tech University Health Sciences Center, El Paso, which has 35 total clinical trials registered on ClinicalTrials.gov.
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