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NCT00442013 · ClinicalTrials.gov registry record · Phase 4

Lansoprazole to Treat Children With Asthma

A Phase 4 study, sponsored by Johns Hopkins University.

Completed
Registry status
Phase 4
Development phase
306
Enrollment target

NCT00442013: Completed Phase 4 study, sponsored by Johns Hopkins University.

NCT00442013 is a Phase 4 study that has completed, run by Johns Hopkins University. The registered enrollment target is 306 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (41% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

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The verdict

NCT00442013, a Phase 4 study, has completed, sponsored by Johns Hopkins University.

COMPLETED
Registry status
Phase 4
Development phase
306 participants
Enrollment target

Study Summary

Many individuals with asthma also experience gastroesophageal reflux disease (GERD), a condition in which excess stomach acid flows backwards into the esophagus. This study will evaluate the effectiveness of lansoprazole, a medication commonly used to treat GERD in improving asthma control and reducing symptoms in children with poorly controlled asthma.

Primary Outcome

Score ranges from 0 to 6, a lower score indicated better asthma control. Scores above 1.5 are indicative of poor asthma control; score obtained from questionnaire with 6 questions related to asthma control and FEV (amount of air expired in the first second during a forced expiratory maneuver); number presents an average of the change from baseline to all follow-up points

Interventions

  • DRUG Matching placebo
  • DRUG Lansoprazole

Trial Details

FieldValue
Enrollment Target 306 participants
Start Date 2007-03
Est. Completion 2011-08
Phase Phase 4
Johns Hopkins University

1,448 total trials

What the finished NCT00442013 record still lists

NCT00442013 is an interventional study that assigns participants to a tested intervention. The registered 306 participants enrollment target is mid-sized for trials with a published cap, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (41% lower).

The record links to 0 conditions, and to 2 interventions - of which Matching placebo is the first listed.

NCT00442013 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00442013 about?

NCT00442013 is a clinical study titled "Lansoprazole to Treat Children With Asthma". Many individuals with asthma also experience gastroesophageal reflux disease (GERD), a condition in which excess stomach acid flows backwards into the esophagus. This study will evaluate the effectiveness of lansoprazole, a medication commonly used to treat GERD in improving asthma control and reduc...

What is the current status of trial NCT00442013?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 306 participants. The study started on 2007-03. Estimated completion is 2011-08.

What interventions are being tested in trial NCT00442013?

The interventions under investigation include: Matching placebo (DRUG), Lansoprazole (DRUG).

Who is sponsoring clinical trial NCT00442013?

This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00442013's enrollment target sits among peer trials

306 264th of 2000 higher than 1,737 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00442013, the US trial registry maintained by the National Library of Medicine. NCT00442013 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.