Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT00440180 · ClinicalTrials.gov registry record · Phase 3
Aromatase Inhibitors in the Treatment of Male Infertility
A Phase 3 study, sponsored by University of Utah.
- Terminated
- Registry status
- Phase 3
- Development phase
- 20
- Enrollment target
NCT00440180: Clinical Trial Phase 3 study, sponsored by University of Utah.
NCT00440180 is a Phase 3 study that was terminated before completion, run by University of Utah. The registered enrollment target is 20 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00440180, a Phase 3 study, was terminated before completion, sponsored by University of Utah.
- TERMINATED
- Registry status
- Phase 3
- Development phase
- 20 participants
- Enrollment target
Study Summary
Obesity is associated with an increase in blood levels of estrogen. Estrogen or "female hormone" is believed to have a negative effect on sperm production. Aromatase inhibitors such as anastrozole work to decrease the production of estrogen and increase testosterone in the body. By decreasing the level of estrogen, sperm production should improve. In this study, the investigators will try to determine the benefit of anastrozole in obese men and follow pregnancy outcomes.
Primary Outcome
Partner pregnancy rate during study participation
Interventions
- DRUG Placebo
- DRUG Anastrozole
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2007-03 |
| Est. Completion | 2014-06 |
| Phase | Phase 3 |
Why NCT00440180 stopped before completion
NCT00440180 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (97% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT00440180 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00440180 about?
NCT00440180 is a clinical study titled "Aromatase Inhibitors in the Treatment of Male Infertility". Obesity is associated with an increase in blood levels of estrogen. Estrogen or "female hormone" is believed to have a negative effect on sperm production. Aromatase inhibitors such as anastrozole work to decrease the production of estrogen and increase testosterone in the body. By decreasing the le...
What is the current status of trial NCT00440180?
This trial is currently terminated. It is a Phase 3 study. The enrollment target is 20 participants. The study started on 2007-03. Estimated completion is 2014-06.
What interventions are being tested in trial NCT00440180?
The interventions under investigation include: Placebo (DRUG), Anastrozole (DRUG).
Who is sponsoring clinical trial NCT00440180?
This trial is sponsored by University of Utah, which has 818 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00440180's enrollment target sits among peer trials
20 1956th of 2000 higher than 32 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT00573339 · 20 participants
Cardiac Magnetic Resonance Imaging (MRI) Normal Reference Control Group Testing
- NCT00692939 · 20 participants · Phase 1
Autologous Stem Cell Transplantation for Crohn's Disease
- NCT00967785 · 20 participants · Phase 1
A Phase I Study of Mozobil in the Treatment of Patients With WHIMS
- NCT01406691 · 20 participants · Phase 4
Light Flashes to Treat Delayed Sleep Phase Disorder (DSPD)
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia