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NCT00438178 · ClinicalTrials.gov registry record · Phase 1
Safety and Efficacy of Obatoclax Mesylate (GX15-070MS) for the Treatment of Hematological Malignancies
A Phase 1 study, sponsored by Gemin X.
- Completed
- Registry status
- Phase 1
- Development phase
- 44
- Enrollment target
NCT00438178: Completed Phase 1 study, sponsored by Gemin X.
NCT00438178 is a Phase 1 study that has completed, run by Gemin X. The registered enrollment target is 44 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (27% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00438178, a Phase 1 study, has completed, sponsored by Gemin X.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 44 participants
- Enrollment target
Study Summary
Defects in the apoptotic process can lead to the onset of cancer by allowing cells to grow unchecked when an oncogneic signal is present. Obatoclax is designed to restore apoptosis through inhibition of the Bcl-2 family of proteins, thereby reinstating the natural process of cell death that is often inhibited in cancer cells.
Interventions
- DRUG Obatoclax mesylate (GX15-070MS)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 44 participants |
| Start Date | 2005-10 |
| Phase | Phase 1 |
What the finished NCT00438178 record still lists
NCT00438178 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 44 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (27% lower).
The record links to 0 conditions, and to 1 intervention - of which Obatoclax mesylate (GX15-070MS) is the first listed.
NCT00438178 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00438178 about?
NCT00438178 is a clinical study titled "Safety and Efficacy of Obatoclax Mesylate (GX15-070MS) for the Treatment of Hematological Malignancies". Defects in the apoptotic process can lead to the onset of cancer by allowing cells to grow unchecked when an oncogneic signal is present. Obatoclax is designed to restore apoptosis through inhibition of the Bcl-2 family of proteins, thereby reinstating the natural process of cell death that is often...
What is the current status of trial NCT00438178?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 44 participants. The study started on 2005-10.
What interventions are being tested in trial NCT00438178?
The interventions under investigation include: Obatoclax mesylate (GX15-070MS) (DRUG).
Who is sponsoring clinical trial NCT00438178?
This trial is sponsored by Gemin X, which has 11 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00438178's enrollment target sits among peer trials
44 1086th of 2000 higher than 901 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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