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NCT00437424 · ClinicalTrials.gov registry record · Phase 1

A Study of Brivanib (BMS-582664) in Patients With Liver Cancer and Mild, Moderate or Severe Liver Dysfunction

A Phase 1 study, sponsored by Bristol-Myers Squibb.

Completed
Registry status
Phase 1
Development phase
24
Enrollment target

NCT00437424: Completed Phase 1 study, sponsored by Bristol-Myers Squibb.

NCT00437424 is a Phase 1 study that has completed, run by Bristol-Myers Squibb. The registered enrollment target is 24 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (60% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00437424, a Phase 1 study, has completed, sponsored by Bristol-Myers Squibb.

COMPLETED
Registry status
Phase 1
Development phase
24 participants
Enrollment target

Study Summary

The primary purpose of this protocol is to determine the effect of BMS-582664 on patients with hepatocellular carcinoma with varying levels of hepatic impairment

Interventions

  • DRUG Brivanib

Trial Details

FieldValue
Enrollment Target 24 participants
Start Date 2007-07
Est. Completion 2010-06
Phase Phase 1
Bristol-Myers Squibb

1,025 total trials

What the finished NCT00437424 record still lists

NCT00437424 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (60% lower).

The record links to 0 conditions, and to 1 intervention - of which Brivanib is the first listed.

NCT00437424 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00437424 about?

NCT00437424 is a clinical study titled "A Study of Brivanib (BMS-582664) in Patients With Liver Cancer and Mild, Moderate or Severe Liver Dysfunction". The primary purpose of this protocol is to determine the effect of BMS-582664 on patients with hepatocellular carcinoma with varying levels of hepatic impairment

What is the current status of trial NCT00437424?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 24 participants. The study started on 2007-07. Estimated completion is 2010-06.

What interventions are being tested in trial NCT00437424?

The interventions under investigation include: Brivanib (DRUG).

Who is sponsoring clinical trial NCT00437424?

This trial is sponsored by Bristol-Myers Squibb, which has 1,025 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00437424's enrollment target sits among peer trials

24 1520th of 2000 higher than 405 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00437424, the US trial registry maintained by the National Library of Medicine. NCT00437424 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.