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NCT00436605 · ClinicalTrials.gov registry record · Phase 2

Dasatinib in Treating Patients With Stage III Melanoma That Cannot Be Removed By Surgery or Stage IV Melanoma

A Phase 2 study, sponsored by National Cancer Institute (NCI).

Completed
Registry status
Phase 2
Development phase
39
Enrollment target

NCT00436605: Completed Phase 2 study, sponsored by National Cancer Institute (NCI).

NCT00436605 is a Phase 2 study that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 39 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (71% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

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The verdict

NCT00436605, a Phase 2 study, has completed, sponsored by National Cancer Institute (NCI).

COMPLETED
Registry status
Phase 2
Development phase
39 participants
Enrollment target

Study Summary

This phase II trial is studying how well dasatinib works in treating patients with stage III melanoma that cannot be removed by surgery or stage IV melanoma. Dasatinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

Primary Outcome

Only those patients who have measurable disease present at baseline, have received at least one course of therapy, and have had their disease re-evaluated will be considered evaluable for response. A Simon's optimum two-stage design will be used.

Interventions

  • DRUG dasatinib

Trial Details

FieldValue
Enrollment Target 39 participants
Start Date 2006-12
Est. Completion 2010-11
Phase Phase 2
National Cancer Institute (NCI)

3,257 total trials

What the finished NCT00436605 record still lists

NCT00436605 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 39 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (71% lower).

The record links to 0 conditions, and to 1 intervention - of which dasatinib is the first listed.

NCT00436605 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00436605 about?

NCT00436605 is a clinical study titled "Dasatinib in Treating Patients With Stage III Melanoma That Cannot Be Removed By Surgery or Stage IV Melanoma". This phase II trial is studying how well dasatinib works in treating patients with stage III melanoma that cannot be removed by surgery or stage IV melanoma. Dasatinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

What is the current status of trial NCT00436605?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 39 participants. The study started on 2006-12. Estimated completion is 2010-11.

What interventions are being tested in trial NCT00436605?

The interventions under investigation include: dasatinib (DRUG).

Who is sponsoring clinical trial NCT00436605?

This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00436605's enrollment target sits among peer trials

39 1459th of 2000 higher than 534 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00436605, the US trial registry maintained by the National Library of Medicine. NCT00436605 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.