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NCT00434473 · ClinicalTrials.gov registry record · Phase 2
IMPACTS Trial: Investigation of the Modulation of Phospholipase in Acute Chest Syndrome
A Phase 2 study, sponsored by Anthera Pharmaceuticals.
- Completed
- Registry status
- Phase 2
- Development phase
- 30
- Enrollment target
NCT00434473: Completed Phase 2 study, sponsored by Anthera Pharmaceuticals.
NCT00434473 is a Phase 2 study that has completed, run by Anthera Pharmaceuticals. The registered enrollment target is 30 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (77% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00434473, a Phase 2 study, has completed, sponsored by Anthera Pharmaceuticals.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 30 participants
- Enrollment target
Study Summary
The study will be conducted at 15-20 US centers in a randomized, placebo-controlled, double-blind fashion. Enrollees will be hospitalized sickle cell disease (SCD) patients at-risk for acute chest syndrome (ACS) based on the presence of vaso-occlusive crisis (VOC), fever (T ≥38.0°C) and serum sPLA2 concentration ≥50 ng/mL.
Interventions
- OTHER Placebo
- DRUG A-001
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2006-12 |
| Est. Completion | 2009-12 |
| Phase | Phase 2 |
What the finished NCT00434473 record still lists
NCT00434473 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (77% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT00434473 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00434473 about?
NCT00434473 is a clinical study titled "IMPACTS Trial: Investigation of the Modulation of Phospholipase in Acute Chest Syndrome". The study will be conducted at 15-20 US centers in a randomized, placebo-controlled, double-blind fashion. Enrollees will be hospitalized sickle cell disease (SCD) patients at-risk for acute chest syndrome (ACS) based on the presence of vaso-occlusive crisis (VOC), fever (T ≥38.0°C) and serum sPLA2 ...
What is the current status of trial NCT00434473?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 30 participants. The study started on 2006-12. Estimated completion is 2009-12.
What interventions are being tested in trial NCT00434473?
The interventions under investigation include: Placebo (OTHER), A-001 (DRUG).
Who is sponsoring clinical trial NCT00434473?
This trial is sponsored by Anthera Pharmaceuticals, which has 16 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00434473's enrollment target sits among peer trials
30 1582nd of 2000 higher than 332 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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