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NCT00433043 · ClinicalTrials.gov registry record · Phase 4
BOAT: Beta Blocker Uptitration With OptiVol After Cardiac Resynchronization Therapy (CRT)
A Phase 4 study, sponsored by St. Luke's-Roosevelt Hospital Center.
- Terminated
- Registry status
- Phase 4
- Development phase
- 2
- Enrollment target
NCT00433043: Clinical Trial Phase 4 study, sponsored by St. Luke's-Roosevelt Hospital Center.
NCT00433043 is a Phase 4 study that was terminated before completion, run by St. Luke's-Roosevelt Hospital Center. The registered enrollment target is 2 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00433043, a Phase 4 study, was terminated before completion, sponsored by St. Luke's-Roosevelt Hospital Center.
- TERMINATED
- Registry status
- Phase 4
- Development phase
- 2 participants
- Enrollment target
Study Summary
Many heart failure patients are unable to reach target beta blocker doses. This study will address whether cardiac resynchronization therapy (CRT) will enable uptitration of beta-blockers to target doses and whether it will favorably affect remodeling by reducing left ventricular end systolic volume (LVESV), with measurable clinical benefit, beyond CRT alone (without changes in beta-blocker dose).
Interventions
- DRUG Beta blocker (carvedilol or metoprolol succinate)
- PROCEDURE CRT (cardiac resynchronization therapy)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 2 participants |
| Start Date | 2007-01 |
| Est. Completion | 2009-05 |
| Phase | Phase 4 |
Why NCT00433043 stopped before completion
NCT00433043 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 2 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (100% lower).
The record links to 0 conditions, and to 2 interventions - of which Beta blocker (carvedilol or metoprolol succinate) is the first listed.
NCT00433043 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00433043 about?
NCT00433043 is a clinical study titled "BOAT: Beta Blocker Uptitration With OptiVol After Cardiac Resynchronization Therapy (CRT)". Many heart failure patients are unable to reach target beta blocker doses. This study will address whether cardiac resynchronization therapy (CRT) will enable uptitration of beta-blockers to target doses and whether it will favorably affect remodeling by reducing left ventricular end systolic volume...
What is the current status of trial NCT00433043?
This trial is currently terminated. It is a Phase 4 study. The enrollment target is 2 participants. The study started on 2007-01. Estimated completion is 2009-05.
What interventions are being tested in trial NCT00433043?
The interventions under investigation include: Beta blocker (carvedilol or metoprolol succinate) (DRUG), CRT (cardiac resynchronization therapy) (PROCEDURE).
Who is sponsoring clinical trial NCT00433043?
This trial is sponsored by St. Luke's-Roosevelt Hospital Center, which has 57 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00433043's enrollment target sits among peer trials
2 1998th of 2000 higher than 1 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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