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NCT00430573 · ClinicalTrials.gov registry record · Phase 2
Efficacy of D-Cycloserine for Enhancing the Effects of CBT for Substance Use
A Phase 2 study, sponsored by Boston University Charles River Campus.
- Terminated
- Registry status
- Phase 2
- Development phase
- 15
- Enrollment target
NCT00430573: Clinical Trial Phase 2 study, sponsored by Boston University Charles River Campus.
NCT00430573 is a Phase 2 study that was terminated before completion, run by Boston University Charles River Campus. The registered enrollment target is 15 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (89% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00430573, a Phase 2 study, was terminated before completion, sponsored by Boston University Charles River Campus.
- TERMINATED
- Registry status
- Phase 2
- Development phase
- 15 participants
- Enrollment target
Study Summary
This study examines whether isolated doses of d-cycloserine enhance the efficacy of an exposure-based cognitive-behavioral treatment for chronic and treatment refractory substance dependence.
Primary Outcome
The primary outcome assessment for this study was the percentage of oral toxicology swabs that were positive of illicit substances. Participants completed these swabs at each assessment point, as well as at each study therapy session. Toxicology swabs were supervised by study staff and used oral specimen collection to screen for opiates, methadone, cocaine, benzodiazepines, amphetamines, THC, and barbiturates.
Interventions
- DRUG Placebo
- DRUG D-cycloserine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 15 participants |
| Start Date | 2007-02 |
| Est. Completion | 2009-06 |
| Phase | Phase 2 |
Why NCT00430573 stopped before completion
NCT00430573 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (89% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT00430573 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00430573 about?
NCT00430573 is a clinical study titled "Efficacy of D-Cycloserine for Enhancing the Effects of CBT for Substance Use". This study examines whether isolated doses of d-cycloserine enhance the efficacy of an exposure-based cognitive-behavioral treatment for chronic and treatment refractory substance dependence.
What is the current status of trial NCT00430573?
This trial is currently terminated. It is a Phase 2 study. The enrollment target is 15 participants. The study started on 2007-02. Estimated completion is 2009-06.
What interventions are being tested in trial NCT00430573?
The interventions under investigation include: Placebo (DRUG), D-cycloserine (DRUG).
Who is sponsoring clinical trial NCT00430573?
This trial is sponsored by Boston University Charles River Campus, which has 104 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00430573's enrollment target sits among peer trials
15 1919th of 2000 higher than 60 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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