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NCT00429169 · ClinicalTrials.gov registry record · Phase 4
Paroxetine/Bupropion in Suicide Attempters/Ideators With Major Depression
A Phase 4 study, sponsored by New York State Psychiatric Institute.
- Terminated
- Registry status
- Phase 4
- Development phase
- 101
- Enrollment target
NCT00429169: Clinical Trial Phase 4 study, sponsored by New York State Psychiatric Institute.
NCT00429169 is a Phase 4 study that was terminated before completion, run by New York State Psychiatric Institute. The registered enrollment target is 101 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (81% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00429169, a Phase 4 study, was terminated before completion, sponsored by New York State Psychiatric Institute.
- TERMINATED
- Registry status
- Phase 4
- Development phase
- 101 participants
- Enrollment target
Study Summary
The primary study comparing effectiveness for suicidal ideation and/or behavior of two antidepressant medications in depressed patients who have attempted suicide or are currently experiencing suicidal thoughts has been completed. A secondary study component using functional magnetic resonance imaging (fMRI) to investigate different medication effects on reward processing in the same sample is ongoing.
Primary Outcome
Change in neuropsychological measure of impulsivity. Computer-based task involving induction of a dominant response tendency and testing of the subject's ability to withhold responding to less frequent non-target stimuli.
Interventions
- DRUG Bupropion
- DRUG Paroxetine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 101 participants |
| Start Date | 2004-06 |
| Est. Completion | 2013-01 |
| Phase | Phase 4 |
Why NCT00429169 stopped before completion
NCT00429169 is an interventional study that assigns participants to a tested intervention. The registered 101 participants enrollment target is mid-sized for trials with a published cap, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (81% lower).
The record links to 0 conditions, and to 2 interventions - of which Bupropion is the first listed.
NCT00429169 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00429169 about?
NCT00429169 is a clinical study titled "Paroxetine/Bupropion in Suicide Attempters/Ideators With Major Depression". The primary study comparing effectiveness for suicidal ideation and/or behavior of two antidepressant medications in depressed patients who have attempted suicide or are currently experiencing suicidal thoughts has been completed. A secondary study component using functional magnetic resonance imag...
What is the current status of trial NCT00429169?
This trial is currently terminated. It is a Phase 4 study. The enrollment target is 101 participants. The study started on 2004-06. Estimated completion is 2013-01.
What interventions are being tested in trial NCT00429169?
The interventions under investigation include: Bupropion (DRUG), Paroxetine (DRUG).
Who is sponsoring clinical trial NCT00429169?
This trial is sponsored by New York State Psychiatric Institute, which has 364 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00429169's enrollment target sits among peer trials
101 766th of 2000 higher than 1,231 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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