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NCT00420927 · ClinicalTrials.gov registry record · Phase 4

Study of the Optimal Protocol for Methotrexate and Adalimumab Combination Therapy in Early Rheumatoid Arthritis

A Phase 4 study, sponsored by Abbott.

Completed
Registry status
Phase 4
Development phase
1,032
Enrollment target

NCT00420927 is a Phase 4 study that has completed, run by Abbott. The registered enrollment target is 1,032 participants.

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The verdict

NCT00420927, a Phase 4 study, has completed, sponsored by Abbott.

COMPLETED
Registry status
Phase 4
Development phase
1,032 participants
Enrollment target

Study Summary

This study compared the safety and efficacy of combination therapy with adalimumab plus methotrexate (MTX) to that of MTX monotherapy (i.e., placebo plus MTX) in subjects with early rheumatoid arthritis (RA).

Interventions

  • BIOLOGICAL placebo
  • DRUG methotrexate
  • BIOLOGICAL adalimumab

Trial Details

FieldValue
Enrollment Target 1,032 participants
Start Date 2006-12
Est. Completion 2010-07
Phase Phase 4

Sponsor

Abbott

181 total trials

What the Registry Record Tells You About NCT00420927

The ClinicalTrials.gov registry entry for NCT00420927 describes a study currently listed as completed, categorized as Phase 4. The registered enrollment target is 1,032 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Abbott, which has 181 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which placebo is the first listed.

NCT00420927 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00420927 about?

NCT00420927 is a clinical study titled "Study of the Optimal Protocol for Methotrexate and Adalimumab Combination Therapy in Early Rheumatoid Arthritis". This study compared the safety and efficacy of combination therapy with adalimumab plus methotrexate (MTX) to that of MTX monotherapy (i.e., placebo plus MTX) in subjects with early rheumatoid arthritis (RA).

What is the current status of trial NCT00420927?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 1,032 participants. The study started on 2006-12. Estimated completion is 2010-07.

What interventions are being tested in trial NCT00420927?

The interventions under investigation include: placebo (BIOLOGICAL), methotrexate (DRUG), adalimumab (BIOLOGICAL).

Who is sponsoring clinical trial NCT00420927?

This trial is sponsored by Abbott, which has 181 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.