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NCT00415493 · ClinicalTrials.gov registry record · NA
Nasal Physiologic Reactivity of Nonallergic Rhinitics to Cold Air Provocation
A NA study, sponsored by Associated Scientists to Help Minimize Allergies.
- Completed
- Registry status
- NA
- Development phase
- 24
- Enrollment target
NCT00415493: Completed NA study, sponsored by Associated Scientists to Help Minimize Allergies.
NCT00415493 is a NA study that has completed, run by Associated Scientists to Help Minimize Allergies. The registered enrollment target is 24 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00415493, a NA study, has completed, sponsored by Associated Scientists to Help Minimize Allergies.
- COMPLETED
- Registry status
- NA
- Development phase
- 24 participants
- Enrollment target
Study Summary
This study seeks to compare patients with vasomotor rhinitis ("perennial nonallergic rhinitis," "idiopathic rhinitis") with normal controls with respect to their nasal physiologic reactivity to cold air challenge. Ten vasomotor rhinitis (VMR) patients with nasal symptoms triggered predominantly by cold air, four VMR patients with symptoms triggered predominantly by chemicals, and ten nonallergic, non-rhinitic control subjects will be studied.
Primary Outcome
Net proportional change in nasal airway resistance, pre- to post-exposure, cold air minus warm air day, calculated as a time-weighted average over the 1.0 h post-exposure. At each time point (pre-exposure, immediately post-exposure, and at 15-, 30-, 45- and 60 minutes post-exposure), nasal airway resistance (in Pa/L/sec) was measured in triplicate. The average of each of these measures was taken for each time point. The time-weighted average of these averages was then calculated for the post-exp
Interventions
- OTHER Cold-dry air provocation
- OTHER Warm-moist air provocation
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2006-12 |
| Est. Completion | 2008-05 |
| Phase | NA |
What the finished NCT00415493 record still lists
NCT00415493 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 2 interventions - of which Cold-dry air provocation is the first listed.
NCT00415493 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00415493 about?
NCT00415493 is a clinical study titled "Nasal Physiologic Reactivity of Nonallergic Rhinitics to Cold Air Provocation". This study seeks to compare patients with vasomotor rhinitis ("perennial nonallergic rhinitis," "idiopathic rhinitis") with normal controls with respect to their nasal physiologic reactivity to cold air challenge. Ten vasomotor rhinitis (VMR) patients with nasal symptoms triggered predominantly by c...
What is the current status of trial NCT00415493?
This trial is currently completed. It is a NA study. The enrollment target is 24 participants. The study started on 2006-12. Estimated completion is 2008-05.
What interventions are being tested in trial NCT00415493?
The interventions under investigation include: Cold-dry air provocation (OTHER), Warm-moist air provocation (OTHER).
Who is sponsoring clinical trial NCT00415493?
This trial is sponsored by Associated Scientists to Help Minimize Allergies, which has 3 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00415493's enrollment target sits among peer trials
24 1736th of 2000 higher than 246 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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