Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00413153 · ClinicalTrials.gov registry record · NA

Metabolic Effects of Switching Kaletra to Boosted Reyataz

A NA study, sponsored by Massachusetts General Hospital.

Completed
Registry status
NA
Development phase
15
Enrollment target

NCT00413153: Completed NA study, sponsored by Massachusetts General Hospital.

NCT00413153 is a NA study that has completed, run by Massachusetts General Hospital. The registered enrollment target is 15 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist → Add completion date to calendar (.ics) →

The verdict

NCT00413153, a NA study, has completed, sponsored by Massachusetts General Hospital.

COMPLETED
Registry status
NA
Development phase
15 participants
Enrollment target

Study Summary

To study the effects of switching from Kaletra to Boosted Reyataz on glucose, lipids and fat in HIV-infected patients.

Primary Outcome

6 month mean and standard deviation for glucose uptake into anterior thigh muscle as measured by FDG/PET scanning during euglycemic hyperinsulinemic clamp. During the hyperinsulinemic conditions of the clamp, glucose and 18-FDG \[labeled glucose\] are taken up by muscle. The quantity of 18-FDG taken up is measured by the PET scan. Although there are no well-accepted norms for this measurement, a higher value indicates that more glucose is being taken up by (or "trafficked to") muscle. Increased

Interventions

  • DRUG atazanavir/ritonavir
  • DRUG lopinavir/ritonavir

Trial Details

FieldValue
Enrollment Target 15 participants
Start Date 2006-05
Est. Completion 2008-12
Phase NA
Massachusetts General Hospital

2,032 total trials

What the finished NCT00413153 record still lists

NCT00413153 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).

The record links to 0 conditions, and to 2 interventions - of which atazanavir/ritonavir is the first listed.

NCT00413153 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00413153 about?

NCT00413153 is a clinical study titled "Metabolic Effects of Switching Kaletra to Boosted Reyataz". To study the effects of switching from Kaletra to Boosted Reyataz on glucose, lipids and fat in HIV-infected patients.

What is the current status of trial NCT00413153?

This trial is currently completed. It is a NA study. The enrollment target is 15 participants. The study started on 2006-05. Estimated completion is 2008-12.

What interventions are being tested in trial NCT00413153?

The interventions under investigation include: atazanavir/ritonavir (DRUG), lopinavir/ritonavir (DRUG).

Who is sponsoring clinical trial NCT00413153?

This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00413153's enrollment target sits among peer trials

15 1881st of 2000 higher than 92 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT01889381 · 15 participants · Phase 2

    Human Craniomaxillofacial Allotransplantation

  • NCT02530073 · 15 participants · NA

    Trial of Fetoscopic Endoluminal Tracheal Occlusion (FETO) for CDH

  • NCT02535936 · 15 participants · NA

    Cortical Plasticity in Spastic Diplegia After Selective Dorsal Rhizotomy

  • NCT02918474 · 15 participants · NA

    Decision Making Tool in Supporting Decision Making in Contralateral Prophylactic Mastectomy in Patients With Newly Diagnosed Breast Cancer

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT00413153, the US trial registry maintained by the National Library of Medicine. NCT00413153 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.