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NCT00411801 · ClinicalTrials.gov registry record · Phase 3

Safety and Efficacy Study to Compare Uniplas With Cryosupernatant Plasma in Thrombotic Thrombocytopenic Purpura (TTP)

A Phase 3 study, sponsored by Octapharma.

Terminated
Registry status
Phase 3
Development phase
8
Enrollment target

NCT00411801: Clinical Trial Phase 3 study, sponsored by Octapharma.

NCT00411801 is a Phase 3 study that was terminated before completion, run by Octapharma. The registered enrollment target is 8 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00411801, a Phase 3 study, was terminated before completion, sponsored by Octapharma.

TERMINATED
Registry status
Phase 3
Development phase
8 participants
Enrollment target

Study Summary

Prior to the use of plasma products, thrombotic thrombocytopenic purpura (TTP) was usually a fatal condition. During plasma exchange therapy, patients need transfusion plasma that is blood group specific. Transfusing a patient with an incorrect blood group may have fatal consequences. Uniplas is a universally applicable human plasma, which can be administered irrespective of the patient's blood group. This study will test the safety and efficacy of Uniplas in comparison to cryosupernatant plasma in treatment of patients with TTP.

Primary Outcome

Log platelet count was reported in units, where 1 unit = 10\^9/L platelets.

Interventions

  • BIOLOGICAL Uniplas
  • BIOLOGICAL Cryosupernatant plasma

Trial Details

FieldValue
Enrollment Target 8 participants
Start Date 2007-05
Est. Completion 2008-02
Phase Phase 3
Octapharma

43 total trials

Why NCT00411801 stopped before completion

NCT00411801 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 8 participants, a relatively small participant target, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (99% lower).

The record links to 0 conditions, and to 2 interventions - of which Uniplas is the first listed.

NCT00411801 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00411801 about?

NCT00411801 is a clinical study titled "Safety and Efficacy Study to Compare Uniplas With Cryosupernatant Plasma in Thrombotic Thrombocytopenic Purpura (TTP)". Prior to the use of plasma products, thrombotic thrombocytopenic purpura (TTP) was usually a fatal condition. During plasma exchange therapy, patients need transfusion plasma that is blood group specific. Transfusing a patient with an incorrect blood group may have fatal consequences. Uniplas is a u...

What is the current status of trial NCT00411801?

This trial is currently terminated. It is a Phase 3 study. The enrollment target is 8 participants. The study started on 2007-05. Estimated completion is 2008-02.

What interventions are being tested in trial NCT00411801?

The interventions under investigation include: Uniplas (BIOLOGICAL), Cryosupernatant plasma (BIOLOGICAL).

Who is sponsoring clinical trial NCT00411801?

This trial is sponsored by Octapharma, which has 43 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00411801's enrollment target sits among peer trials

8 1993rd of 2000 higher than 6 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00411801, the US trial registry maintained by the National Library of Medicine. NCT00411801 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.