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NCT00410774 · ClinicalTrials.gov registry record · Phase 1

Gemcitabine and Bevacizumab in Treating Patients With Pancreatic Cancer That Has Been Completely Removed By Surgery

A Phase 1 study, sponsored by University of California, San Francisco.

Terminated
Registry status
Phase 1
Development phase
20
Enrollment target

NCT00410774: Clinical Trial Phase 1 study, sponsored by University of California, San Francisco.

NCT00410774 is a Phase 1 study that was terminated before completion, run by University of California, San Francisco. The registered enrollment target is 20 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (67% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00410774, a Phase 1 study, was terminated before completion, sponsored by University of California, San Francisco.

TERMINATED
Registry status
Phase 1
Development phase
20 participants
Enrollment target

Study Summary

RATIONALE: Drugs used in chemotherapy, such as gemcitabine, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Monoclonal antibodies, such as bevacizumab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread. Others find tumor cells and help kill them or carry tumor-killing substances to them. Bevacizumab may also stop the growth of pancreatic cancer by blocking blood flow to the tumor. Giving gemcitabine and bevacizumab after surgery may kill any tumor cells that remain after surgery. PURPOSE: This phase I/II trial is studying the side effects of gemcitabine and bevacizumab and to see how well they work in treating patients with pancreatic cancer that has been completely removed by surgery.

Interventions

  • BIOLOGICAL bevacizumab
  • PROCEDURE adjuvant therapy
  • DRUG gemcitabine hydrochloride

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2006-07
Est. Completion 2007-10
Phase Phase 1

Why NCT00410774 stopped before completion

NCT00410774 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (67% lower).

The record links to 0 conditions, and to 3 interventions - of which bevacizumab is the first listed.

NCT00410774 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00410774 about?

NCT00410774 is a clinical study titled "Gemcitabine and Bevacizumab in Treating Patients With Pancreatic Cancer That Has Been Completely Removed By Surgery". RATIONALE: Drugs used in chemotherapy, such as gemcitabine, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Monoclonal antibodies, such as bevacizumab, can block tumor growth in different ways. Some block the ability of tumor c...

What is the current status of trial NCT00410774?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 20 participants. The study started on 2006-07. Estimated completion is 2007-10.

What interventions are being tested in trial NCT00410774?

The interventions under investigation include: bevacizumab (BIOLOGICAL), adjuvant therapy (PROCEDURE), gemcitabine hydrochloride (DRUG).

Who is sponsoring clinical trial NCT00410774?

This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00410774's enrollment target sits among peer trials

20 1629th of 2000 higher than 285 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00410774, the US trial registry maintained by the National Library of Medicine. NCT00410774 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.