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NCT00408525 · ClinicalTrials.gov registry record · Phase 1
Donepezil and Brain Activity Patterns in Those at Risk For Alzheimer's Disease
A Phase 1 study, sponsored by Vanderbilt University.
- Completed
- Registry status
- Phase 1
- Development phase
- 41
- Enrollment target
NCT00408525: Completed Phase 1 study, sponsored by Vanderbilt University.
NCT00408525 is a Phase 1 study that has completed, run by Vanderbilt University. The registered enrollment target is 41 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (32% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00408525, a Phase 1 study, has completed, sponsored by Vanderbilt University.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 41 participants
- Enrollment target
Study Summary
The purpose of the study is to examine patterns of brain activity in people who are at risk for memory problems (e.g., Alzheimer's disease or dementia)before and after the medication donepezil. Although genetic testing will be done, the results will not be shared with study participants. Once the genetic testing is completed subjects may continue to the second phase of the study. During this time they will be asked to take the medication donepezil (which is approved by the FDA for the treatment of Alzheimer's disease). Donepezil is not FDA approved for healthy volunteers and is therefore considered investigational in this study.
Interventions
- DRUG donepezil
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 41 participants |
| Start Date | 2006-12 |
| Est. Completion | 2012-08-24 |
| Phase | Phase 1 |
What the finished NCT00408525 record still lists
NCT00408525 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 41 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (32% lower).
The record links to 0 conditions, and to 1 intervention - of which donepezil is the first listed.
NCT00408525 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00408525 about?
NCT00408525 is a clinical study titled "Donepezil and Brain Activity Patterns in Those at Risk For Alzheimer's Disease". The purpose of the study is to examine patterns of brain activity in people who are at risk for memory problems (e.g., Alzheimer's disease or dementia)before and after the medication donepezil. Although genetic testing will be done, the results will not be shared with study participants. Once the g...
What is the current status of trial NCT00408525?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 41 participants. The study started on 2006-12. Estimated completion is 2012-08-24.
What interventions are being tested in trial NCT00408525?
The interventions under investigation include: donepezil (DRUG).
Who is sponsoring clinical trial NCT00408525?
This trial is sponsored by Vanderbilt University, which has 430 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00408525's enrollment target sits among peer trials
41 1125th of 2000 higher than 871 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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