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NCT00407745 · ClinicalTrials.gov registry record · Phase 3
A 17-Week Trial To Assess Pregabalin For The Treatment Of Nerve Pain Due To Spinal Cord Injury
A Phase 3 study of Spinal Cord Injuries and Neuralgia, sponsored by Pfizer's Upjohn has merged with Mylan to form Viatris.
- Completed
- Registry status
- Phase 3
- Development phase
- 220
- Enrollment target
- 20
- Study locations
NCT00407745: Completed Phase 3 study of Spinal Cord Injuries and Neuralgia, sponsored by Pfizer's Upjohn has merged with Mylan to form Viatris.
NCT00407745 is a Phase 3 study of Spinal Cord Injuries and Neuralgia that has completed, run by Pfizer's Upjohn has merged with Mylan to form Viatris. The registered enrollment target is 220 participants, above the 61-participant average among 202 other Spinal Cord Injuries trials with a reported enrollment target (261% higher). The trial reports 20 study locations across 11 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00407745, a Phase 3 study of Spinal Cord Injuries and Neuralgia, has completed, sponsored by Pfizer's Upjohn has merged with Mylan to form Viatris.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 220 participants
- Enrollment target
- 20
- Study locations
Study Summary
The purpose of this study is to evaluate if pregabalin relieves nerve pain associated with spinal cord injury compared to placebo (pill that contains no active medicine). This study will also evaluate the safety of pregabalin in this patient population.
Primary Outcome
DAAC was derived from participant's daily pain diary, where pain was measured on an 11-point Numerical Rating Scale (NRS-Pain)ranging from 0 (did not interfere with sleep) to 10 (completely interfered \[unable to sleep due to pain\]). The DAAC was calculated as the mean of all daily pain diary rating post baseline minus the baseline score then multiplied by the proportion of the planned study duration completed by the participant.
Conditions Studied
Interventions
- DRUG placebo
- DRUG pregabalin
Study Locations (20)
California
- Pfizer Investigational Site - Fresno
- Pfizer Investigational Site - Napa
- Pfizer Investigational Site - Northridge
- Pfizer Investigational Site - Pasadena
Arizona
- Pfizer Investigational Site - Phoenix
- Pfizer Investigational Site - Phoenix
- Pfizer Investigational Site - Phoenix
Florida
- Pfizer Investigational Site - Miami
- Pfizer Investigational Site - Miami
- Pfizer Investigational Site - Orlando
New York
- Pfizer Investigational Site - New York
- Pfizer Investigational Site - White Plains
Pennsylvania
- Pfizer Investigational Site - Johnstown
- Pfizer Investigational Site - Philadelphia
Indiana
- Pfizer Investigational Site - Indianapolis
Kansas
- Pfizer Investigational Site - Overland Park
Michigan
- Pfizer Investigational Site - Detroit
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 220 participants |
| Start Date | 2007-01 |
| Est. Completion | 2011-02 |
| Phase | Phase 3 |
What the finished NCT00407745 record still lists
NCT00407745 is an interventional study that assigns participants to a tested intervention. The registered 220 participants enrollment target is mid-sized for trials with a published cap, above the 61-participant average among 202 other Spinal Cord Injuries trials with a reported enrollment target (261% higher).
The record links to 2 conditions, with Spinal Cord Injuries appearing as the primary indexed condition, and to 2 interventions - of which placebo is the first listed.
NCT00407745 names 20 study sites across 11 states, led by California, Arizona, Florida.
Frequently Asked Questions
What is clinical trial NCT00407745 about?
NCT00407745 is a clinical study titled "A 17-Week Trial To Assess Pregabalin For The Treatment Of Nerve Pain Due To Spinal Cord Injury". The purpose of this study is to evaluate if pregabalin relieves nerve pain associated with spinal cord injury compared to placebo (pill that contains no active medicine). This study will also evaluate the safety of pregabalin in this patient population.
What is the current status of trial NCT00407745?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 220 participants. The study started on 2007-01. Estimated completion is 2011-02.
What conditions does trial NCT00407745 study?
This clinical trial studies the following conditions: Spinal Cord Injuries, Neuralgia.
What interventions are being tested in trial NCT00407745?
The interventions under investigation include: placebo (DRUG), pregabalin (DRUG).
Who is sponsoring clinical trial NCT00407745?
This trial is sponsored by Pfizer's Upjohn has merged with Mylan to form Viatris, which has 158 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00407745 being conducted?
This trial has 20 study locations across Arizona, California, Florida, Indiana, Kansas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Spinal Cord Injuries
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00407745's enrollment target sits among peer trials
220 10th of 202 higher than 193 of 202 other Spinal Cord Injuries trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Spinal Cord Injuries trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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