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NCT00407303 · ClinicalTrials.gov registry record · Phase 1
Safety and Efficacy of Obatoclax Mesylate (GX15-070MS) in Combination With Bortezomib for the Treatment of Relapsed or Refractory Mantle Cell Lymphoma (MCL)
A Phase 1 study, sponsored by Gemin X.
- Completed
- Registry status
- Phase 1
- Development phase
- 24
- Enrollment target
NCT00407303 is a Phase 1 study that has completed, run by Gemin X. The registered enrollment target is 24 participants.
The verdict
NCT00407303, a Phase 1 study, has completed, sponsored by Gemin X.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 24 participants
- Enrollment target
Study Summary
Defects in the apoptotic process can lead to the onset of cancer by allowing cells to grow unchecked when an oncogenic signal is present. Obatoclax is designed to restore apoptosis through inhibition of the Bcl-2 family of proteins, thereby reinstating the natural process of cell death that is often inhibited in cancer cells.
Interventions
- DRUG Bortezomib
- DRUG Obatoclax mesylate
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2006-10 |
| Est. Completion | 2009-11 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00407303
The ClinicalTrials.gov registry entry for NCT00407303 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 24 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Gemin X, which has 11 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Bortezomib is the first listed.
NCT00407303 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT00407303 about?
NCT00407303 is a clinical study titled "Safety and Efficacy of Obatoclax Mesylate (GX15-070MS) in Combination With Bortezomib for the Treatment of Relapsed or Refractory Mantle Cell Lymphoma (MCL)". Defects in the apoptotic process can lead to the onset of cancer by allowing cells to grow unchecked when an oncogenic signal is present. Obatoclax is designed to restore apoptosis through inhibition of the Bcl-2 family of proteins, thereby reinstating the natural process of cell death that is often...
What is the current status of trial NCT00407303?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 24 participants. The study started on 2006-10. Estimated completion is 2009-11.
What interventions are being tested in trial NCT00407303?
The interventions under investigation include: Bortezomib (DRUG), Obatoclax mesylate (DRUG).
Who is sponsoring clinical trial NCT00407303?
This trial is sponsored by Gemin X, which has 11 total clinical trials registered on ClinicalTrials.gov.
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