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NCT00405405 · ClinicalTrials.gov registry record · Phase 1
Phase I of Biologics and Chemoradiation Therapy for Advanced Head and Neck Cancer
A Phase 1 study, sponsored by Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University.
- Completed
- Registry status
- Phase 1
- Development phase
- 13
- Enrollment target
NCT00405405: Completed Phase 1 study, sponsored by Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University.
NCT00405405 is a Phase 1 study that has completed, run by Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University. The registered enrollment target is 13 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (78% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00405405, a Phase 1 study, has completed, sponsored by Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 13 participants
- Enrollment target
Study Summary
To determine a safe and effective doses of two biologic drugs, erlotinib and bevacizumab when used with chemotherapy and radiation therapy in advanced head and neck cancer
Primary Outcome
To determine if bevacizumab and erlotinib can be safely combined with chemoradiotherapy for advanced head and neck cancer.
Interventions
- DRUG Bevacizumab
- DRUG Docetaxel
- DRUG Cisplatin
- RADIATION Radiotherapy
- DRUG Erlotinib
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 13 participants |
| Start Date | 2006-12 |
| Est. Completion | 2010-06 |
| Phase | Phase 1 |
What the finished NCT00405405 record still lists
NCT00405405 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 13 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (78% lower).
The record links to 0 conditions, and to 5 interventions - of which Bevacizumab is the first listed.
NCT00405405 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00405405 about?
NCT00405405 is a clinical study titled "Phase I of Biologics and Chemoradiation Therapy for Advanced Head and Neck Cancer". To determine a safe and effective doses of two biologic drugs, erlotinib and bevacizumab when used with chemotherapy and radiation therapy in advanced head and neck cancer
What is the current status of trial NCT00405405?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 13 participants. The study started on 2006-12. Estimated completion is 2010-06.
What interventions are being tested in trial NCT00405405?
The interventions under investigation include: Bevacizumab (DRUG), Docetaxel (DRUG), Cisplatin (DRUG), Radiotherapy (RADIATION), Erlotinib (DRUG).
Who is sponsoring clinical trial NCT00405405?
This trial is sponsored by Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University, which has 138 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00405405's enrollment target sits among peer trials
13 1847th of 2000 higher than 149 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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