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NCT00402467 · ClinicalTrials.gov registry record · Phase 2

An Oral, Direct Factor Xa Inhibitor, BAY59-7939, for Prophylaxis Against Venous Thromboembolism After Total Knee Replacement: a Dose-Ranging Study

A Phase 2 study, sponsored by Bayer.

Completed
Registry status
Phase 2
Development phase
613
Enrollment target

NCT00402467 is a Phase 2 study that has completed, run by Bayer. The registered enrollment target is 613 participants.

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The verdict

NCT00402467, a Phase 2 study, has completed, sponsored by Bayer.

COMPLETED
Registry status
Phase 2
Development phase
613 participants
Enrollment target

Study Summary

The study drug, BAY59-7939, is a new drug currently being tested in the prevention of VTE. It directly inhibits factor Xa, a blood component in the pathway which leads to coagulation (clotting of blood cells). It is available as a tablet. The purpose of this study is to compare the safety and efficacy of BAY59-7939 with the safety and efficacy of the licensed drug Enoxaparin. Enoxaparin, a so-called low molecular heparin, is approved and widely used in the area of thromboprophylaxis and will be given once daily subcutaneously. In this study 4 different doses of the investigational drug BAY59-7939 will be tested in comparison to Enoxaparin. You will receive during the study either one of the following BAY59-7939 treatments or Enoxaparin. The following doses of BAY59-7939 will be tested: Dose I ; Dose II, Dose III, Dose IV. This study will run for approximately 7 months in a number of countries. In total, up to 600 patients may participate in this study.

Interventions

  • DRUG Rivaroxaban (BAY59-7939)
  • DRUG Rivaroxaban, (BAY59-7939)
  • DRUG Enoxaparine

Trial Details

FieldValue
Enrollment Target 613 participants
Start Date 2004-02
Est. Completion 2004-11
Phase Phase 2

Sponsor

Bayer

591 total trials

What the Registry Record Tells You About NCT00402467

The ClinicalTrials.gov registry entry for NCT00402467 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 613 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Bayer, which has 591 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which Rivaroxaban (BAY59-7939) is the first listed.

NCT00402467 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00402467 about?

NCT00402467 is a clinical study titled "An Oral, Direct Factor Xa Inhibitor, BAY59-7939, for Prophylaxis Against Venous Thromboembolism After Total Knee Replacement: a Dose-Ranging Study". The study drug, BAY59-7939, is a new drug currently being tested in the prevention of VTE. It directly inhibits factor Xa, a blood component in the pathway which leads to coagulation (clotting of blood cells). It is available as a tablet. The purpose of this study is to compare the safety and effica...

What is the current status of trial NCT00402467?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 613 participants. The study started on 2004-02. Estimated completion is 2004-11.

What interventions are being tested in trial NCT00402467?

The interventions under investigation include: Rivaroxaban (BAY59-7939) (DRUG), Rivaroxaban, (BAY59-7939) (DRUG), Enoxaparine (DRUG).

Who is sponsoring clinical trial NCT00402467?

This trial is sponsored by Bayer, which has 591 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.