Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT00391001 · ClinicalTrials.gov registry record · Phase 1
Taurine in Adolescents With Bipolar Disorder
A Phase 1 study, sponsored by Cambridge Health Alliance.
- Terminated
- Registry status
- Phase 1
- Development phase
- 4
- Enrollment target
NCT00391001: Clinical Trial Phase 1 study, sponsored by Cambridge Health Alliance.
NCT00391001 is a Phase 1 study that was terminated before completion, run by Cambridge Health Alliance. The registered enrollment target is 4 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (93% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00391001, a Phase 1 study, was terminated before completion, sponsored by Cambridge Health Alliance.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 4 participants
- Enrollment target
Study Summary
Recently, McLean hospital conducted a 4 month taurine study which showed a reduction in mania ratings. As a follow-up to the preliminary taurine study, and complementary to the currently ongoing double-blind, placebo-controlled trial for taurine in adults with bipolar disorder, this study will target adolescent bipolar subjects (type I) with symptoms of mania or mixed mania. To our knowledge, this would be the first study to evaluate the effects of the novel compound taurine in adolescent subjects with bipolar disorder. We hypothesize there will be a positive response in some adolescents from taurine treatment, and this positive response will be greater than that expected by chance. This study may demonstrate that taurine is a well-tolerated and effective adjunct treatment for mania in bipolar disorder.
Interventions
- DRUG Taurine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 4 participants |
| Start Date | 2006-02 |
| Est. Completion | 2007-08 |
| Phase | Phase 1 |
Why NCT00391001 stopped before completion
NCT00391001 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 4 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (93% lower).
The record links to 0 conditions, and to 1 intervention - of which Taurine is the first listed.
NCT00391001 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00391001 about?
NCT00391001 is a clinical study titled "Taurine in Adolescents With Bipolar Disorder". Recently, McLean hospital conducted a 4 month taurine study which showed a reduction in mania ratings. As a follow-up to the preliminary taurine study, and complementary to the currently ongoing double-blind, placebo-controlled trial for taurine in adults with bipolar disorder, this study will targe...
What is the current status of trial NCT00391001?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 4 participants. The study started on 2006-02. Estimated completion is 2007-08.
What interventions are being tested in trial NCT00391001?
The interventions under investigation include: Taurine (DRUG).
Who is sponsoring clinical trial NCT00391001?
This trial is sponsored by Cambridge Health Alliance, which has 45 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00391001's enrollment target sits among peer trials
4 1995th of 2000 higher than 2 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia