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NCT00388453 · ClinicalTrials.gov registry record · NA
Efficacy of Dx-pH Probe in Diagnosing Extra-esophageal Reflux Disease
A NA study, sponsored by Vanderbilt University Medical Center.
- Completed
- Registry status
- NA
- Development phase
- 47
- Enrollment target
NCT00388453: Completed NA study, sponsored by Vanderbilt University Medical Center.
NCT00388453 is a NA study that has completed, run by Vanderbilt University Medical Center. The registered enrollment target is 47 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00388453, a NA study, has completed, sponsored by Vanderbilt University Medical Center.
- COMPLETED
- Registry status
- NA
- Development phase
- 47 participants
- Enrollment target
Study Summary
The purpose of this study is to establish the clinical application of a new device that records pH changes in the hypopharynx. The investigators also aim to compare the consistency of distal esophageal pH with hypopharyngeal pH using both the "short" and the "long" catheters in patients.
Primary Outcome
The three study groups underwent dual pH measurements of the oropharyngeal as well as esophageal acid exposure employing the regular length probe for the oropharynx and the custom-designed long probe for the distal esophagus. The reason for the custom-designed esophageal measurement was to ensure that events noted in the oropharynx originated distally and were of gastric source. Measurements for the two locations were time synchronized to ensure accuracy. Calculations were based on length of tim
Interventions
- DEVICE Dx-pH Probe
- PROCEDURE Manometry
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 47 participants |
| Start Date | 2006-10 |
| Est. Completion | 2013-07 |
| Phase | NA |
What the finished NCT00388453 record still lists
NCT00388453 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 47 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).
The record links to 0 conditions, and to 2 interventions - of which Dx-pH Probe is the first listed.
NCT00388453 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00388453 about?
NCT00388453 is a clinical study titled "Efficacy of Dx-pH Probe in Diagnosing Extra-esophageal Reflux Disease". The purpose of this study is to establish the clinical application of a new device that records pH changes in the hypopharynx. The investigators also aim to compare the consistency of distal esophageal pH with hypopharyngeal pH using both the "short" and the "long" catheters in patients.
What is the current status of trial NCT00388453?
This trial is currently completed. It is a NA study. The enrollment target is 47 participants. The study started on 2006-10. Estimated completion is 2013-07.
What interventions are being tested in trial NCT00388453?
The interventions under investigation include: Dx-pH Probe (DEVICE), Manometry (PROCEDURE).
Who is sponsoring clinical trial NCT00388453?
This trial is sponsored by Vanderbilt University Medical Center, which has 677 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00388453's enrollment target sits among peer trials
47 1400th of 2000 higher than 599 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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