Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT00387270 · ClinicalTrials.gov registry record · Phase 1
Safety Study of the Novel Drug Dimebon to Treat Patients With Huntington's Disease
A Phase 1 study, sponsored by Medivation.
- Completed
- Registry status
- Phase 1
- Development phase
- 9
- Enrollment target
NCT00387270: Completed Phase 1 study, sponsored by Medivation.
NCT00387270 is a Phase 1 study that has completed, run by Medivation. The registered enrollment target is 9 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (85% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00387270, a Phase 1 study, has completed, sponsored by Medivation.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 9 participants
- Enrollment target
Study Summary
This study is being conducted to determine the safety and tolerability of Dimebon in people with Huntington's disease after short-term exposure (one week) and after longer exposure (three months). Also, the study will assess whether or not there is an effect of Dimebon on the symptoms of Huntington's disease, including cognitive (thinking abilities), motor (movement), behavior, and overall functioning.
Interventions
- DRUG Dimebon
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 9 participants |
| Start Date | 2006-10 |
| Est. Completion | 2007-03 |
| Phase | Phase 1 |
What the finished NCT00387270 record still lists
NCT00387270 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 9 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (85% lower).
The record links to 0 conditions, and to 1 intervention - of which Dimebon is the first listed.
NCT00387270 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00387270 about?
NCT00387270 is a clinical study titled "Safety Study of the Novel Drug Dimebon to Treat Patients With Huntington's Disease". This study is being conducted to determine the safety and tolerability of Dimebon in people with Huntington's disease after short-term exposure (one week) and after longer exposure (three months). Also, the study will assess whether or not there is an effect of Dimebon on the symptoms of Huntington'...
What is the current status of trial NCT00387270?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 9 participants. The study started on 2006-10. Estimated completion is 2007-03.
What interventions are being tested in trial NCT00387270?
The interventions under investigation include: Dimebon (DRUG).
Who is sponsoring clinical trial NCT00387270?
This trial is sponsored by Medivation, which has 9 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00387270's enrollment target sits among peer trials
9 1955th of 2000 higher than 42 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia