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NCT00385177 · ClinicalTrials.gov registry record · Phase 1

Phase 1 Dose Escalation Study of SN2310 Injectable Emulsion in Patients With Advanced Solid Tumors

A Phase 1 study, sponsored by Achieve Life Sciences.

Completed
Registry status
Phase 1
Development phase
61
Enrollment target

NCT00385177: Completed Phase 1 study, sponsored by Achieve Life Sciences.

NCT00385177 is a Phase 1 study that has completed, run by Achieve Life Sciences. The registered enrollment target is 61 participants, roughly in line with the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00385177, a Phase 1 study, has completed, sponsored by Achieve Life Sciences.

COMPLETED
Registry status
Phase 1
Development phase
61 participants
Enrollment target

Study Summary

This is a Phase 1 open-label study of SN2310 Injectable Emulsion in patients with advanced solid malignancies. The study is designed to determine the maximum tolerated dose and dose-limiting toxicity of SN2310 Injectable Emulsion, and to characterize the pharmacokinetics of SN2310 and SN-38 following intravenous administration of SN2310 Injectable Emulsion. Additionally, evaluation of side effects as a function of dose, and observation of any anti-tumor effects of SN2310 Injectable Emulsion will be made.

Interventions

  • DRUG SN2310 Injectable Emulsion

Trial Details

FieldValue
Enrollment Target 61 participants
Start Date 2006-09
Est. Completion 2009-05
Phase Phase 1
Achieve Life Sciences

17 total trials

What the finished NCT00385177 record still lists

NCT00385177 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 61 participants, a relatively small participant target, roughly in line with the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target.

The record links to 0 conditions, and to 1 intervention - of which SN2310 Injectable Emulsion is the first listed.

NCT00385177 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00385177 about?

NCT00385177 is a clinical study titled "Phase 1 Dose Escalation Study of SN2310 Injectable Emulsion in Patients With Advanced Solid Tumors". This is a Phase 1 open-label study of SN2310 Injectable Emulsion in patients with advanced solid malignancies. The study is designed to determine the maximum tolerated dose and dose-limiting toxicity of SN2310 Injectable Emulsion, and to characterize the pharmacokinetics of SN2310 and SN-38 followin...

What is the current status of trial NCT00385177?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 61 participants. The study started on 2006-09. Estimated completion is 2009-05.

What interventions are being tested in trial NCT00385177?

The interventions under investigation include: SN2310 Injectable Emulsion (DRUG).

Who is sponsoring clinical trial NCT00385177?

This trial is sponsored by Achieve Life Sciences, which has 17 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00385177's enrollment target sits among peer trials

61 828th of 2000 higher than 1,170 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00385177, the US trial registry maintained by the National Library of Medicine. NCT00385177 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.