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NCT00383890 · ClinicalTrials.gov registry record · Phase 3

A Safety and Efficacy Study of Dexmedetomidine in Patients Requiring Sedation for Elective Awake Fiberoptic Intubation

A Phase 3 study, sponsored by Hospira, now a wholly owned subsidiary of Pfizer.

Completed
Registry status
Phase 3
Development phase
124
Enrollment target

NCT00383890: Completed Phase 3 study, sponsored by Hospira, now a wholly owned subsidiary of Pfizer.

NCT00383890 is a Phase 3 study that has completed, run by Hospira, now a wholly owned subsidiary of Pfizer. The registered enrollment target is 124 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (84% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00383890, a Phase 3 study, has completed, sponsored by Hospira, now a wholly owned subsidiary of Pfizer.

COMPLETED
Registry status
Phase 3
Development phase
124 participants
Enrollment target

Study Summary

The purpose of this study is to evaluate the safety and efficacy of dexmedetomidine versus placebo used for sedation during elective awake fiberoptic intubation.

Primary Outcome

Sedation levels (Ramsay Sedation Scale \[RSS\] score ≥2 \[Patient is cooperative, oriented and tranquil\])

Interventions

  • DRUG Placebo
  • DRUG Dexmedetomidine HCL Injection

Trial Details

FieldValue
Enrollment Target 124 participants
Start Date 2006-08
Est. Completion 2007-03
Phase Phase 3

What the finished NCT00383890 record still lists

NCT00383890 is an interventional study that assigns participants to a tested intervention. The registered 124 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (84% lower).

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT00383890 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00383890 about?

NCT00383890 is a clinical study titled "A Safety and Efficacy Study of Dexmedetomidine in Patients Requiring Sedation for Elective Awake Fiberoptic Intubation". The purpose of this study is to evaluate the safety and efficacy of dexmedetomidine versus placebo used for sedation during elective awake fiberoptic intubation.

What is the current status of trial NCT00383890?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 124 participants. The study started on 2006-08. Estimated completion is 2007-03.

What interventions are being tested in trial NCT00383890?

The interventions under investigation include: Placebo (DRUG), Dexmedetomidine HCL Injection (DRUG).

Who is sponsoring clinical trial NCT00383890?

This trial is sponsored by Hospira, now a wholly owned subsidiary of Pfizer, which has 15 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00383890's enrollment target sits among peer trials

124 1610th of 2000 higher than 386 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00383890, the US trial registry maintained by the National Library of Medicine. NCT00383890 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.