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NCT00379548 · ClinicalTrials.gov registry record · NA
Changes in Inflammatory State in Asian Americans Changing From Traditional Asian Diets to American Diet - a Pilot Study
A NA study, sponsored by Joslin Diabetes Center.
- Completed
- Registry status
- NA
- Development phase
- 50
- Enrollment target
NCT00379548: Completed NA study, sponsored by Joslin Diabetes Center.
NCT00379548 is a NA study that has completed, run by Joslin Diabetes Center. The registered enrollment target is 50 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00379548, a NA study, has completed, sponsored by Joslin Diabetes Center.
- COMPLETED
- Registry status
- NA
- Development phase
- 50 participants
- Enrollment target
Study Summary
We hypothesize that Asian Americans compared to Caucasians, will be at higher risk of developing a pro-inflammatory state that may contribute to the development of heart disease and diabetes when they change from a traditional Asian diet to a typical Western diet. These inflammatory responses will be reflected by the activation of monocytes as measured by protein kinase C (PKC), a known activator of monocytes. We also hypothesize that the changes of these inflammatory responses in the gingival crevicular fluid (GCF) will reflect similar changes of these markers in the plasma and monocytes. Specific aims: 1. To compare the inflammatory responses (primarily PKC activation in monocytes), between Far-East Asian Americans and Caucasian Americans, when they change from a traditional Asian diet to a typical American diet. 2. To correlate the biochemical changes of inflammatory responses in the plasma and monocytes with those in the gingival crevicular fluid (GCF).
Interventions
- BEHAVIORAL 2 groups of population responding to 2 types of diets
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2005-11 |
| Est. Completion | 2014-09 |
| Phase | NA |
What the finished NCT00379548 record still lists
NCT00379548 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower).
The record links to 0 conditions, and to 1 intervention - of which 2 groups of population responding to 2 types of diets is the first listed.
NCT00379548 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00379548 about?
NCT00379548 is a clinical study titled "Changes in Inflammatory State in Asian Americans Changing From Traditional Asian Diets to American Diet - a Pilot Study". We hypothesize that Asian Americans compared to Caucasians, will be at higher risk of developing a pro-inflammatory state that may contribute to the development of heart disease and diabetes when they change from a traditional Asian diet to a typical Western diet. These inflammatory responses will b...
What is the current status of trial NCT00379548?
This trial is currently completed. It is a NA study. The enrollment target is 50 participants. The study started on 2005-11. Estimated completion is 2014-09.
What interventions are being tested in trial NCT00379548?
The interventions under investigation include: 2 groups of population responding to 2 types of diets (BEHAVIORAL).
Who is sponsoring clinical trial NCT00379548?
This trial is sponsored by Joslin Diabetes Center, which has 73 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00379548's enrollment target sits among peer trials
50 1279th of 2000 higher than 622 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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