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NCT00377455 · ClinicalTrials.gov registry record · Phase 2
Placebo Controlled Trial of Bosentan in Scleroderma Patients
A Phase 2 study, sponsored by Georgetown University.
- Terminated
- Registry status
- Phase 2
- Development phase
- 5
- Enrollment target
NCT00377455: Clinical Trial Phase 2 study, sponsored by Georgetown University.
NCT00377455 is a Phase 2 study that was terminated before completion, run by Georgetown University. The registered enrollment target is 5 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00377455, a Phase 2 study, was terminated before completion, sponsored by Georgetown University.
- TERMINATED
- Registry status
- Phase 2
- Development phase
- 5 participants
- Enrollment target
Study Summary
The purpose of this study is to determine whether the drug Bosentan improves exercise tolerance in scleroderma patients.
Primary Outcome
The total exercise time measured using the exercise echocardiogram is evaluated with the standard Bruce Stress Protocol, and this will be determined after 16 weeks on the study medication.
Interventions
- DRUG Placebo
- DRUG Bosentan
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 5 participants |
| Start Date | 2006-09 |
| Est. Completion | 2010-03 |
| Phase | Phase 2 |
Why NCT00377455 stopped before completion
NCT00377455 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 5 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (96% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT00377455 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00377455 about?
NCT00377455 is a clinical study titled "Placebo Controlled Trial of Bosentan in Scleroderma Patients". The purpose of this study is to determine whether the drug Bosentan improves exercise tolerance in scleroderma patients.
What is the current status of trial NCT00377455?
This trial is currently terminated. It is a Phase 2 study. The enrollment target is 5 participants. The study started on 2006-09. Estimated completion is 2010-03.
What interventions are being tested in trial NCT00377455?
The interventions under investigation include: Placebo (DRUG), Bosentan (DRUG).
Who is sponsoring clinical trial NCT00377455?
This trial is sponsored by Georgetown University, which has 227 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00377455's enrollment target sits among peer trials
5 2000th of 2000 the lowest of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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