Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT00377403 · ClinicalTrials.gov registry record · Phase 4
Treatment of Acute Sinusitis
A Phase 4 study, sponsored by Washington University School of Medicine.
- Completed
- Registry status
- Phase 4
- Development phase
- 172
- Enrollment target
NCT00377403 is a Phase 4 study that has completed, run by Washington University School of Medicine. The registered enrollment target is 172 participants.
The verdict
NCT00377403, a Phase 4 study, has completed, sponsored by Washington University School of Medicine.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 172 participants
- Enrollment target
Study Summary
This study will compare the symptom relief provided by 5 cold medicines versus the symptom relief provided by the same 5 cold medicines plus the antibiotic, amoxicillin, in people who have sinus infections. Treatment with amoxicillin may be more effective than treatment with cold medicines alone. Two hundred adult volunteers, aged 18 to 70 years old, with sinus infections will participate in this study for 28 days. Volunteers will receive a 10-day course of either amoxicillin or placebo (substance containing no medication). In addition, all volunteers will receive pain medication, a chest decongestant, nasal decongestants, and cough medicine as needed. Volunteers will be interviewed by telephone on days 0, 3, 7, 10, and 28 following the start of treatment. The study will look at quality of life factors such as change in functional status (ability to perform daily activities) and symptoms, recurrence of the infection, satisfaction with care, and the direct costs of treatment.
Interventions
- DRUG Acetaminophen
- DRUG Amoxicillin
- DRUG Guaifenesin
- DRUG Dextromethorphan hydrobromide with guaifenesin
- DRUG Pseudoephedrine Sustained Action
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 172 participants |
| Start Date | 2006-10 |
| Est. Completion | 2010-08 |
| Phase | Phase 4 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00377403
The ClinicalTrials.gov registry entry for NCT00377403 describes a study currently listed as completed, categorized as Phase 4. The registered enrollment target is 172 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Washington University School of Medicine, which has 1,502 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 5 interventions - of which Acetaminophen is the first listed.
NCT00377403 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT00377403 about?
NCT00377403 is a clinical study titled "Treatment of Acute Sinusitis". This study will compare the symptom relief provided by 5 cold medicines versus the symptom relief provided by the same 5 cold medicines plus the antibiotic, amoxicillin, in people who have sinus infections. Treatment with amoxicillin may be more effective than treatment with cold medicines alone. Tw...
What is the current status of trial NCT00377403?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 172 participants. The study started on 2006-10. Estimated completion is 2010-08.
What interventions are being tested in trial NCT00377403?
The interventions under investigation include: Acetaminophen (DRUG), Amoxicillin (DRUG), Guaifenesin (DRUG), Dextromethorphan hydrobromide with guaifenesin (DRUG), Pseudoephedrine Sustained Action (DRUG).
Who is sponsoring clinical trial NCT00377403?
This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
Explore more on PlainTrial
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.