Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT00377247 · ClinicalTrials.gov registry record · Phase 1
Active Immunization of Patients With Carcinoma of Oral Cavity or Oropharynx With Autologous Dendritic Cells Transfected With DNA From Autologous Tumor
A Phase 1 study, sponsored by University of Pittsburgh.
- Terminated
- Registry status
- Phase 1
- Development phase
- 5
- Enrollment target
NCT00377247: Clinical Trial Phase 1 study, sponsored by University of Pittsburgh.
NCT00377247 is a Phase 1 study that was terminated before completion, run by University of Pittsburgh. The registered enrollment target is 5 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (92% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00377247, a Phase 1 study, was terminated before completion, sponsored by University of Pittsburgh.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 5 participants
- Enrollment target
Study Summary
The primary goal of this study is to determine if the vaccine can be safely given to subjects, and to see what side effects occur (both good and bad) when they are given this experimental tumor vaccine. During this study, investigators intend to watch for tumor response while examining the effects of this vaccine on the body's immune system after it is given.
Interventions
- BIOLOGICAL autologous monocyte-derived dendritic cells (DC) transfected with DNA
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 5 participants |
| Start Date | 2009-04 |
| Est. Completion | 2009-04 |
| Phase | Phase 1 |
Why NCT00377247 stopped before completion
NCT00377247 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 5 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (92% lower).
The record links to 0 conditions, and to 1 intervention - of which autologous monocyte-derived dendritic cells (DC) transfected with DNA is the first listed.
NCT00377247 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00377247 about?
NCT00377247 is a clinical study titled "Active Immunization of Patients With Carcinoma of Oral Cavity or Oropharynx With Autologous Dendritic Cells Transfected With DNA From Autologous Tumor". The primary goal of this study is to determine if the vaccine can be safely given to subjects, and to see what side effects occur (both good and bad) when they are given this experimental tumor vaccine. During this study, investigators intend to watch for tumor response while examining the effects o...
What is the current status of trial NCT00377247?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 5 participants. The study started on 2009-04. Estimated completion is 2009-04.
What interventions are being tested in trial NCT00377247?
The interventions under investigation include: autologous monocyte-derived dendritic cells (DC) transfected with DNA (BIOLOGICAL).
Who is sponsoring clinical trial NCT00377247?
This trial is sponsored by University of Pittsburgh, which has 1,238 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00377247's enrollment target sits among peer trials
5 1989th of 2000 higher than 6 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia