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NCT00370149 · ClinicalTrials.gov registry record · Phase 4
Study of Catheter-related Infections Using Antibiotic-coated Versus Conventional Catheters in Children
A Phase 4 study, sponsored by Indiana University.
- Terminated
- Registry status
- Phase 4
- Development phase
- 326
- Enrollment target
NCT00370149: Clinical Trial Phase 4 study, sponsored by Indiana University.
NCT00370149 is a Phase 4 study that was terminated before completion, run by Indiana University. The registered enrollment target is 326 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (37% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00370149, a Phase 4 study, was terminated before completion, sponsored by Indiana University.
- TERMINATED
- Registry status
- Phase 4
- Development phase
- 326 participants
- Enrollment target
Study Summary
The primary purpose of the study is to determine if a therapeutic difference exists between central venous catheters impregnated with minocycline and rifampin and conventional catheters not impregnated with antibiotics when used in children at high risk for bloodstream infections (CABSI) after cardiac surgery.
Primary Outcome
Rates of CRBSI defined as 1. micro-organism isolated from a blood culture; 2. Clinical manifestations of infection such as fever (≥38 C) and/or hypotension (defined according to age-related practice guidelines for systolic blood pressure); 3. No apparent source for the bloodstream infection except for the catheter.
Interventions
- DEVICE Antibiotic-impregnated Catheters (M/R)
- DEVICE Non-impregnated Catheters (C/S)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 326 participants |
| Start Date | 2006-09 |
| Est. Completion | 2010-05 |
| Phase | Phase 4 |
Why NCT00370149 stopped before completion
NCT00370149 is an interventional study that assigns participants to a tested intervention. The registered 326 participants enrollment target is mid-sized for trials with a published cap, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (37% lower).
The record links to 0 conditions, and to 2 interventions - of which Antibiotic-impregnated Catheters (M/R) is the first listed.
NCT00370149 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00370149 about?
NCT00370149 is a clinical study titled "Study of Catheter-related Infections Using Antibiotic-coated Versus Conventional Catheters in Children". The primary purpose of the study is to determine if a therapeutic difference exists between central venous catheters impregnated with minocycline and rifampin and conventional catheters not impregnated with antibiotics when used in children at high risk for bloodstream infections (CABSI) after cardi...
What is the current status of trial NCT00370149?
This trial is currently terminated. It is a Phase 4 study. The enrollment target is 326 participants. The study started on 2006-09. Estimated completion is 2010-05.
What interventions are being tested in trial NCT00370149?
The interventions under investigation include: Antibiotic-impregnated Catheters (M/R) (DEVICE), Non-impregnated Catheters (C/S) (DEVICE).
Who is sponsoring clinical trial NCT00370149?
This trial is sponsored by Indiana University, which has 890 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00370149's enrollment target sits among peer trials
326 253rd of 2000 higher than 1,747 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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