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NCT00365781 · ClinicalTrials.gov registry record · Phase 1
Examination of Dermatologic Effects From Subcutaneous Injections of ISIS 113715
A Phase 1 study, sponsored by Ionis Pharmaceuticals.
- Completed
- Registry status
- Phase 1
- Development phase
- 10
- Enrollment target
NCT00365781: Completed Phase 1 study, sponsored by Ionis Pharmaceuticals.
NCT00365781 is a Phase 1 study that has completed, run by Ionis Pharmaceuticals. The registered enrollment target is 10 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (83% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00365781, a Phase 1 study, has completed, sponsored by Ionis Pharmaceuticals.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 10 participants
- Enrollment target
Study Summary
10 healthy volunteers will be enrolled to each receive two subcutaneous injections of ISIS 113715 in the abdomen on Study Day 1. Each subject will receive their two injections within a 5-minute period. On Study Days 2 and 8, each subject's injection sites will be assessed for dermatologic effects. The Isis Project Physician(s) will observe the injection sites on Study Day 2 and may also observe on Study Day 8. Routine clinical chemistry, hematology, and urinalysis tests will be performed on Study Day 1 and Day 8. Subjects will be contacted by telephone on Study Day 30 to monitor for the occurrence of new serious adverse events (SAEs). Thereafter, the subjects will be discharged from the study.
Interventions
- DRUG ISIS 113715
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2006-08 |
| Est. Completion | 2006-09 |
| Phase | Phase 1 |
What the finished NCT00365781 record still lists
NCT00365781 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (83% lower).
The record links to 0 conditions, and to 1 intervention - of which ISIS 113715 is the first listed.
NCT00365781 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00365781 about?
NCT00365781 is a clinical study titled "Examination of Dermatologic Effects From Subcutaneous Injections of ISIS 113715". 10 healthy volunteers will be enrolled to each receive two subcutaneous injections of ISIS 113715 in the abdomen on Study Day 1. Each subject will receive their two injections within a 5-minute period. On Study Days 2 and 8, each subject's injection sites will be assessed for dermatologic effects. T...
What is the current status of trial NCT00365781?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 10 participants. The study started on 2006-08. Estimated completion is 2006-09.
What interventions are being tested in trial NCT00365781?
The interventions under investigation include: ISIS 113715 (DRUG).
Who is sponsoring clinical trial NCT00365781?
This trial is sponsored by Ionis Pharmaceuticals, which has 76 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00365781's enrollment target sits among peer trials
10 1913th of 2000 higher than 46 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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