Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00358982 · ClinicalTrials.gov registry record · Phase 2

Study of MGCD0103 (MG-0103) in Patients With Relapsed or Refractory Hodgkin's Lymphoma

A Phase 2 study, sponsored by Mirati Therapeutics.

Terminated
Registry status
Phase 2
Development phase
51
Enrollment target

NCT00358982: Clinical Trial Phase 2 study, sponsored by Mirati Therapeutics.

NCT00358982 is a Phase 2 study that was terminated before completion, run by Mirati Therapeutics. The registered enrollment target is 51 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (62% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00358982, a Phase 2 study, was terminated before completion, sponsored by Mirati Therapeutics.

TERMINATED
Registry status
Phase 2
Development phase
51 participants
Enrollment target

Study Summary

MGCD0103 is an experimental drug that belongs to a class of drugs known as the histone deacetylase inhibitors, which may restore normal control in cancer cells by affecting the genes and proteins that are being made. Laboratory tests show that this new investigational anti-cancer drug can slow down the growth of human cancer cells in mice; two clinical research studies are currently being performed in humans with cancer and a similar study is being performed in patients with the same disease. The purpose of this study is to find out what effect the experimental drug MGCD0103 has on patients with relapsed and refractory Hodgkin's lymphoma.

Interventions

  • DRUG MGCD0103

Trial Details

FieldValue
Enrollment Target 51 participants
Start Date 2006-08
Est. Completion 2009-01
Phase Phase 2
Mirati Therapeutics

49 total trials

Why NCT00358982 stopped before completion

NCT00358982 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 51 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (62% lower).

The record links to 0 conditions, and to 1 intervention - of which MGCD0103 is the first listed.

NCT00358982 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00358982 about?

NCT00358982 is a clinical study titled "Study of MGCD0103 (MG-0103) in Patients With Relapsed or Refractory Hodgkin's Lymphoma". MGCD0103 is an experimental drug that belongs to a class of drugs known as the histone deacetylase inhibitors, which may restore normal control in cancer cells by affecting the genes and proteins that are being made. Laboratory tests show that this new investigational anti-cancer drug can slow down ...

What is the current status of trial NCT00358982?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 51 participants. The study started on 2006-08. Estimated completion is 2009-01.

What interventions are being tested in trial NCT00358982?

The interventions under investigation include: MGCD0103 (DRUG).

Who is sponsoring clinical trial NCT00358982?

This trial is sponsored by Mirati Therapeutics, which has 49 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00358982's enrollment target sits among peer trials

51 1190th of 2000 higher than 806 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT02701153 · 51 participants · NA

    Phase II Study of 5-Day Hypofractionated Preoperative Radiation Therapy for Soft Tissue Sarcomas: Expansion Cohort

  • NCT03663790 · 51 participants · NA

    Effects of Gait Retraining on Lower Extremity Biomechanics

  • NCT03874052 · 51 participants · Phase 1

    Ruxolitinib in Combination With Venetoclax With and Without Azacitidine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

  • NCT04704661 · 51 participants · Phase 1

    Testing the Combination of Two Anti-cancer Drugs, DS-8201a and AZD6738, for The Treatment of Advanced Solid Tumors Expressing the HER2 Protein or Gene, The DASH Trial

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT00358982, the US trial registry maintained by the National Library of Medicine. NCT00358982 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.