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NCT00358423 · ClinicalTrials.gov registry record · Phase 1
The Effect of Macugen in Patients With Chronic, Post-Operative Cystoid Macular Edema
A Phase 1 study, sponsored by Johns Hopkins University.
- Terminated
- Registry status
- Phase 1
- Development phase
- 1
- Enrollment target
NCT00358423: Clinical Trial Phase 1 study, sponsored by Johns Hopkins University.
NCT00358423 is a Phase 1 study that was terminated before completion, run by Johns Hopkins University. The registered enrollment target is 1 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00358423, a Phase 1 study, was terminated before completion, sponsored by Johns Hopkins University.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 1 participants
- Enrollment target
Study Summary
This research is being done to look at the effects of an experimental drug called pegaptanib (also called Macugen) for the treatment of swelling in the retina (the light sensitive tissue in the back of the eye) that can occur after cataract surgery. Swelling in the retina can lead to blurry vision. The only treatment available for this condition is eye drops that decrease swelling in the back of the eye, but eye drops may not decrease the swelling in everyone. We want to see if pegaptanib can decrease swelling in the retina and improve vision in patients with swelling after cataract surgery.
Interventions
- DRUG Control
- DRUG Pegaptanib Sodium
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1 participants |
| Start Date | 2006-07 |
| Est. Completion | 2007-02 |
| Phase | Phase 1 |
Why NCT00358423 stopped before completion
NCT00358423 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 1 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 2 interventions - of which Control is the first listed.
NCT00358423 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00358423 about?
NCT00358423 is a clinical study titled "The Effect of Macugen in Patients With Chronic, Post-Operative Cystoid Macular Edema". This research is being done to look at the effects of an experimental drug called pegaptanib (also called Macugen) for the treatment of swelling in the retina (the light sensitive tissue in the back of the eye) that can occur after cataract surgery. Swelling in the retina can lead to blurry vision. ...
What is the current status of trial NCT00358423?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 1 participants. The study started on 2006-07. Estimated completion is 2007-02.
What interventions are being tested in trial NCT00358423?
The interventions under investigation include: Control (DRUG), Pegaptanib Sodium (DRUG).
Who is sponsoring clinical trial NCT00358423?
This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00358423's enrollment target sits among peer trials
1 2001st of 2000 the lowest of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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